# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3630319 | B | Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incubated for 100 mins by inorganic phosphate detection assay | Mycolicibacterium smegmatis | 50 | cell-based format | Scientific Literature | ||
2. | ALA3630322 | B | Inhibition of DNA gyrase GyrA/GyrB in Mycobacterium tuberculosis incubated for 30 mins assessed as reduction in supercoiling of relaxed relaxed pBR322 DNA by ethidium bromide staining based agarose gel electrophoresis method | Mycobacterium tuberculosis | 50 | assay format | Scientific Literature | ||
3. | ALA3630438 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv assessed as growth inhibition incubated for 7 days by microplate alamar blue assay | Mycobacterium tuberculosis | 50 | organism-based format | Scientific Literature | ||
4. | ALA3630439 | A | Cytotoxicity against mouse RAW264.7 cells assessed as inhibition of cell viability at 50 uM incubated for 48 hrs at 37 degC by MTT assay relative to control | Mus musculus | 50 | cell-based format | Scientific Literature |