| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3631085 | B | Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assay | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 2. | ALA3631086 | B | Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assay | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 3. | ALA3631087 | B | Selectivity ratio of IC50 for recombinant human IDO to IC50 for recombinant human TDO | Homo sapiens | 18 | assay format | Scientific Literature | ||
| 4. | ALA3631088 | U | Redox cycling activity of the compound assessed as H2O2 production at 50 uM incubated for 15 mins by HRP-PR assay in presence of 0.8 mM DTT | 2 | assay format | Scientific Literature | |||
| 5. | ALA3631089 | U | Redox cycling activity of the compound assessed as H2O2 production incubated for 15 mins by HRP-PR assay in presence of 0.8 mM DTT | 2 | assay format | Scientific Literature | |||
| 6. | ALA3631090 | B | Inhibition of human PTP1B at 10 uM preincubated with protein for 15 mins followed by DiFMUP addition for 1 hr measured by fluorescence analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA3631091 | B | Inhibition of human PTP1B preincubated with protein for 15 mins followed by DiFMUP addition for 1 hr measured by fluorescence analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA3631092 | B | Inhibition of human EGFR incubated for 2 hrs by Kinase-Glo luminescent kinase assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 9. | ALA3631093 | B | Inhibition of recombinant mu-opioid receptor (unknown origin) expressed in CHO cells for 60 mins | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3631094 | B | Inhibition of FLT3 (unknown origin) expressed in Sf9 insect cells for 4 hrs by Kinase-Glo assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA3631095 | B | Displacement of 125I-SDF-1 from human CXCR4 expressed in HEK293 cells incubated for 1.5 hrs by Topcount analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA3631096 | B | Inhibition of Aurora A (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 13. | ALA3631097 | B | Inhibition of Dengue virus type 2 NS2B-NS3 protease | dengue virus type 2 | 2 | assay format | Scientific Literature | ||
| 14. | ALA3631098 | B | Inhibition of human muscle mitochondrial complex 1 by spectrophotometric assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 15. | ALA3631099 | B | Inhibition of catalase (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 16. | ALA3631100 | B | Binding affinity to recombinant human TDO assessed as shift in Soret signal at 2 mM by UV-visible spectra analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA4381980 | B | Inhibition of TDO (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4709780 | B | Inhibition of IDO1 (unknown origin) assessed as reduction in L-kynurenine formation using L-tryptophan as substrate incubated for 30 mins by microplate spectrophotometry analysis | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 19. | ALA4709781 | B | Inhibition of TDO (unknown origin) assessed as reduction in L-kynurenine formation using L-tryptophan as substrate incubated for 30 mins microplate spectrophotometry analysis | Homo sapiens | 38 | single protein format | Scientific Literature |
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