| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3630525 | B | Inhibition of STAT3 in Oncostatin M induced human HeLa cells assessed as accumulation of STAT3 in cytoplasm in presence of IL-6 by Western blot analysis | Homo sapiens | 1 | ALA3627693 | cell-based format | Scientific Literature | |
| 2. | ALA3630526 | B | Inhibition of STAT3 in Oncostatin M induced mouse B9 cells assessed as decrease of phospho-STAT3 in nucleus in presence of IL-6 by Western blot analysis | Mus musculus | 1 | ALA3627693 | cell-based format | Scientific Literature | |
| 3. | ALA3630527 | B | Inhibition of STAT3 in Oncostatin M induced mouse B9 cells assessed as accumulation of STAT3 in cytoplasm in presence of IL-6 by Western blot analysis | Mus musculus | 1 | ALA3627693 | cell-based format | Scientific Literature | |
| 4. | ALA3630528 | B | Inhibition of STAT3 in Oncostatin M induced human HeLa cells assessed as decrease of phospho-STAT3 in nucleus at 100 uM in presence of IL-6 by DAPI staining-based Confocal microscpoic analysis | Homo sapiens | 1 | ALA3627693 | cell-based format | Scientific Literature | |
| 5. | ALA3630529 | B | Inhibition of STAT3 in Oncostatin M induced human HeLa cells assessed as accumulation of STAT3 in cytoplasm at 100 uM in presence of IL-6 by DAPI staining-based Confocal microscpoic analysis | Homo sapiens | 1 | ALA3627693 | cell-based format | Scientific Literature | |
| 6. | ALA3630530 | F | Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell proliferation after 72 hrs by MTT assay | Homo sapiens | 1 | ALA3627693 | cell-based format | Scientific Literature | |
| 7. | ALA3630531 | F | Cytotoxicity against mouse B9 cells assessed as decrease in cell proliferation at 50 uM after 72 hrs by MTT assay | Mus musculus | 1 | ALA3627693 | cell-based format | Scientific Literature | |
| 8. | ALA3630532 | F | Cytotoxicity against human MDA-MB-231 cells transfected with STAT3C assessed as decrease in cell proliferation after 72 hrs by MTT assay | Homo sapiens | 1 | ALA3627693 | cell-based format | Scientific Literature | |
| 9. | ALA3630533 | F | Induction of polarization of C57BL/6 mouse spleen naive CD4+ lymphocytes into Th17 lymphocytes assessed as decrease in ROR-gamma-t transcription at 50 uM | Mus musculus | 1 | ALA3627693 | tissue-based format | Scientific Literature | |
| 10. | ALA3630534 | F | Induction of polarization of C57BL/6 mouse spleen naive CD4+ lymphocytes into Th17 lymphocytes assessed as decrease in FoxP3 transcription at 50 uM | Mus musculus | 1 | ALA3627693 | tissue-based format | Scientific Literature | |
| 11. | ALA3630535 | F | Induction of polarization of C57BL/6 mouse spleen naive CD4+ lymphocytes into Treg lymphocytes assessed as decrease in ROR-gamma-t transcription at 50 uM | Mus musculus | 1 | ALA3627693 | tissue-based format | Scientific Literature | |
| 12. | ALA3630536 | F | Induction of polarization of C57BL/6 mouse spleen naive CD4+ lymphocytes into Treg lymphocytes assessed as decrease in FoxP3 transcription at 50 uM | Mus musculus | 1 | ALA3627693 | tissue-based format | Scientific Literature | |
| 13. | ALA3630537 | F | Induction of polarization of C57BL/6 mouse spleen naive CD4+ lymphocytes into Th1 lymphocytes assessed as decrease in Tbet transcription | Mus musculus | 1 | ALA3627693 | tissue-based format | Scientific Literature | |
| 14. | ALA3630538 | F | Induction IFN-gamma production in human PBL cells co-cultured with HT29 cells at 50 uM after 24 hrs by ELISA | Homo sapiens | 1 | ALA3627693 | cell-based format | Scientific Literature | |
| 15. | ALA3631101 | B | Displacement of fluorescent peptide 5-FAM-G(pTyr)LPQTV-CONH2 from GST-tagged full-length human STAT3 preincubated for 60 mins followed by fluorescent peptide addition measured after 30 mins by fluorescence polarization assay | Homo sapiens | 8 | ALA3627693 | single protein format | Scientific Literature | |
| 16. | ALA3631102 | B | Displacement of fluorescent peptide 5-FAM-G(pTyr)YIKTE- CONH2 from GST-tagged human STAT1b preincubated for 60 mins followed by fluorescent peptide addition measured after 30 mins by fluorescence polarization assay | Homo sapiens | 7 | ALA3627693 | single protein format | Scientific Literature | |
| 17. | ALA3631103 | B | Inhibition of STAT3 (unknown origin) expressed in Oncostatin M induced human HeLa cells at 50 uM incubated for 1 hr by luciferase reporter gene assay | Homo sapiens | 64 | ALA3627693 | cell-based format | Scientific Literature | |
| 18. | ALA3631104 | B | Inhibition of STAT1 (unknown origin) expressed in in IFN-gamma induced human HeLa cells at 50 uM incubated for 1 hr by luciferase reporter gene assay | Homo sapiens | 55 | ALA3627693 | cell-based format | Scientific Literature | |
| 19. | ALA3631105 | B | Inhibition of STAT3 (unknown origin) expressed in Oncostatin M induced human HeLa cells incubated for 1 hr by luciferase reporter gene assay | Homo sapiens | 1 | ALA3627693 | cell-based format | Scientific Literature | |
| 20. | ALA3631106 | B | Inhibition of STAT3 in Oncostatin M induced human HeLa cells assessed as decrease of phospho-STAT3 in nucleus in presence of IL-6 by Western blot analysis | Homo sapiens | 1 | ALA3627693 | cell-based format | Scientific Literature |
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