# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3631965 | F | Antiviral activity against HCV JFH1 infected in human HuH7-J20 cells assessed as inhibition of viral life cycle by measuring secreted alkaline phosphatase level at 10 uM preincubated with cells for 1 hr followed by viral inoculation for 3 hrs measured at 72 hrs relative to control | Hepacivirus hominis | 12 | ALA3627618 | cell-based format | Scientific Literature | |
2. | ALA4147463 | F | Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation at 10 uM after 20 mins by BRET assay relative to beta-PEA | Mus musculus | 3 | ALA4145505 | cell-based format | Scientific Literature | |
3. | ALA4147464 | F | Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay | Mus musculus | 4 | ALA4145505 | cell-based format | Scientific Literature | |
4. | ALA4147465 | F | Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation at 10 uM after 20 mins by BRET assay relative to beta-PEA | Homo sapiens | 2 | ALA4145505 | cell-based format | Scientific Literature | |
5. | ALA4147466 | F | Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay | Homo sapiens | 3 | ALA4145505 | cell-based format | Scientific Literature | |
6. | ALA4147467 | B | Selectivity ratio of EC50 for mouse TAAR1 to EC50 for human TAAR1 | 1 | ALA4145505 | assay format | Scientific Literature | ||
7. | ALA4147468 | F | Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assay | Mus musculus | 10 | ALA4145505 | cell-based format | Scientific Literature |