| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3630140 | B | Inhibition of recombinant human PDE10A assessed as reduction of [3H]-cAMP hydrolysis preincubated for 5 mins followed by [3H]-cAMP addition measured after 20 mins by scintillation proximity assay | Homo sapiens | 22 | ALA3627597 | single protein format | Scientific Literature | |
| 2. | ALA3630141 | B | Inhibition of recombinant human PDE3A assessed as reduction of [3H]-cAMP hydrolysis preincubated for 5 mins followed by [3H]-cAMP addition measured after 20 mins by scintillation proximity assay | Homo sapiens | 22 | ALA3627597 | single protein format | Scientific Literature | |
| 3. | ALA3630142 | B | Inhibition of recombinant human PDE3B assessed as reduction of [3H]-cAMP hydrolysis preincubated for 5 mins followed by [3H]-cAMP addition measured after 20 mins by scintillation proximity assay | Homo sapiens | 22 | ALA3627597 | single protein format | Scientific Literature | |
| 4. | ALA3630143 | B | Inhibition of recombinant human PDE4A assessed as reduction of [3H]-cAMP hydrolysis preincubated for 5 mins followed by [3H]-cAMP addition measured after 20 mins by scintillation proximity assay | Homo sapiens | 22 | ALA3627597 | single protein format | Scientific Literature | |
| 5. | ALA3630144 | B | Inhibition of recombinant human PDE4B assessed as reduction of [3H]-cAMP hydrolysis preincubated for 5 mins followed by [3H]-cAMP addition measured after 20 mins by scintillation proximity assay | Homo sapiens | 22 | ALA3627597 | single protein format | Scientific Literature | |
| 6. | ALA3630145 | B | Selectivity ratio of IC50 for recombinant human PDE3A to IC50 for recombinant human PDE10A | Homo sapiens | 22 | ALA3627597 | assay format | Scientific Literature | |
| 7. | ALA3630146 | B | Selectivity ratio of IC50 for recombinant human PDE3B to IC50 for recombinant human PDE10A | Homo sapiens | 22 | ALA3627597 | assay format | Scientific Literature | |
| 8. | ALA3630147 | B | Selectivity ratio of IC50 for recombinant human PDE4A to IC50 for recombinant human PDE10A | Homo sapiens | 22 | ALA3627597 | assay format | Scientific Literature | |
| 9. | ALA3630257 | B | Selectivity ratio of IC50 for recombinant human PDE4B to IC50 for recombinant human PDE10A | Homo sapiens | 22 | ALA3627597 | assay format | Scientific Literature |
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