# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3630621 | B | Synergistic agonist activity at Wnt/beta-catenin (unknown origin) expressed in Wnt-3A conditioned media stimulated with HEK293 cells incubated for 24 hrs by firefly luciferase based TOPflash reporter assay | Homo sapiens | 42 | ALA3627670 | cell-based format | Scientific Literature | |
2. | ALA3630622 | B | Inhibition of poly-histidine tagged full-length rat ARFGAP1 expressed in Sf9 cells assessed as remaining enzyme activity at 20 uM using purified WT ARF1 pre-loaded with [gamm-32P]-labeled GTP incubated for 5 mins before ARF1-GTP addition followed by 25 mins incubation by scintillation counting method | Rattus norvegicus | 42 | ALA3627670 | cell-based format | Scientific Literature | |
3. | ALA3630623 | B | Inhibition of poly-histidine tagged full-length rat ARFGAP1 expressed in Sf9 cells assessed as remaining enzyme activity at 10 uM using purified WT ARF1 pre-loaded with [gamm-32P]-labeled GTP incubated for 5 mins before ARF1-GTP addition followed by 25 mins incubation by scintillation counting method | Rattus norvegicus | 42 | ALA3627670 | cell-based format | Scientific Literature | |
4. | ALA3630624 | B | Potency index, ratio of EC50 for QS11 to EC50 for test compound for synergistic agonist activity at Wnt/beta-catenin (unknown origin) expressed in Wnt-3A conditioned media stimulated with HEK293 cells incubated for 24 hrs by firefly luciferase based TOPflash reporter assay | Homo sapiens | 1 | ALA3627670 | cell-based format | Scientific Literature |