| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3631240 | Binding | Inhibition of human placental cytosolic 17beta HSD1 using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins by HPLC analysis | Homo sapiens | 49 | ALA3627664 | assay format | Scientific Literature | |
| 2. | ALA3631241 | Binding | Inhibition of human placental microsomal 17beta HSD2 using unlabeled- and labelled [2,4,6,7-3H]-E2 as substrate incubated for 20 mins by HPLC analysis | Homo sapiens | 37 | ALA3627664 | assay format | Scientific Literature | |
| 3. | ALA3631242 | Binding | Selectivity ratio of IC50 for human microsomal 17beta HSD2 to IC50 for human placental cytosolic 17beta HSD1 | Homo sapiens | 37 | ALA3627664 | assay format | Scientific Literature | |
| 4. | ALA3631243 | Binding | Inhibition of recombinant mouse 17beta HSD1 expressed in HEK293 cells using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate at 1 uM incubated for 10 mins by HPLC analysis | Mus musculus | 47 | ALA3627664 | cell-based format | Scientific Literature | |
| 5. | ALA4400641 | Binding | Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysis | Homo sapiens | 16 | ALA4400508 | subcellular format | Scientific Literature | |
| 6. | ALA4400642 | Binding | Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysis | Homo sapiens | 16 | ALA4400508 | assay format | Scientific Literature | |
| 7. | ALA4400643 | Binding | Selectivity factor, ratio of IC50 for human placental cytosolic fraction 17beta-HSD1 to IC50 for human placental microsomal fraction 17beta-HSD2 | Homo sapiens | 16 | ALA4400508 | subcellular format | Scientific Literature | |
| 8. | ALA4400645 | Binding | Inhibition of mouse liver homogenate 17beta-HSD2 at 1 uM using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysis relative to control | Mus musculus | 2 | ALA4400508 | tissue-based format | Scientific Literature | |
| 9. | ALA4400648 | Binding | Inhibition of recombinant mouse 17beta-HSD1 expressed in HEK293 cells at 1 uM using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysis relative to control | Mus musculus | 2 | ALA4400508 | cell-based format | Scientific Literature | |
| 10. | ALA4400659 | ADME | Half life in human liver S9 fraction in presence of NADPH, UDPGA, PAPS | Homo sapiens | 16 | ALA4400508 | subcellular format | Scientific Literature |
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