# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA643073 | B | Inhibitory activity was tested against human recombinant ATP-Citrate Lyase (ACL) enzyme | 1 | ALA1131093 | single protein format | Scientific Literature | ||
2. | ALA643074 | B | Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzyme | 30 | ALA1131093 | single protein format | Scientific Literature | ||
3. | ALA640438 | B | Inhibitory activity was tested against rat ATP-Citrate Lyase (ACL) enzyme | 2 | ALA1131093 | single protein format | Scientific Literature | ||
4. | ALA696881 | F | Inhibition of ATP levels in HepG2 cells was measured at 100 uM concentration. | Homo sapiens | 2 | ALA1131093 | cell-based format | Scientific Literature | |
5. | ALA699381 | F | Inhibition of cholesterol synthesis in HepG2 cells was measured at 100 uM concentration. | Homo sapiens | 2 | ALA1131093 | cell-based format | Scientific Literature | |
6. | ALA699388 | F | Inhibition of fatty acid synthesis in HepG2 cells was measured at 100 uM concentration. | Homo sapiens | 2 | ALA1131093 | cell-based format | Scientific Literature | |
7. | ALA906357 | B | Inhibition of human recombinant ATP-citrate lyase | Homo sapiens | 13 | ALA1139904 | single protein format | Scientific Literature | |
8. | ALA925175 | B | Inhibition of human ATP citrate lyase | Homo sapiens | 1 | ALA1140634 | single protein format | Scientific Literature | |
9. | ALA2169034 | B | Inhibition of rat liver ACLY | Rattus norvegicus | 8 | ALA2163275 | assay format | Scientific Literature | |
10. | ALA2169035 | B | Inhibition of human recombinant ACLY | Homo sapiens | 7 | ALA2163275 | single protein format | Scientific Literature | |
11. | ALA4001976 | B | Competitive inhibition of ATP citrate lyase (unknown origin) using sodium citrate as substrate by ADP-Glo luminescence assay | Homo sapiens | 2 | ALA4000242 | single protein format | Scientific Literature | |
12. | ALA4275778 | B | Inhibition of rat ACLY | Rattus norvegicus | 1 | ALA4270641 | single protein format | Scientific Literature | |
13. | ALA4275779 | B | Inhibition of human ACLY | Homo sapiens | 2 | ALA4270641 | single protein format | Scientific Literature | |
14. | ALA4275782 | F | In vivo inhibition of ACLY in po dosed rat assessed as reduction in plasma cholesterol level after 7 days relative to control | Rattus norvegicus | 1 | ALA4270641 | organism-based format | Scientific Literature | |
15. | ALA4275783 | F | In vivo inhibition of ACLY in po dosed rat assessed as reduction in plasma triglyceride level after 7 days relative to control | Rattus norvegicus | 1 | ALA4270641 | organism-based format | Scientific Literature | |
16. | ALA4275784 | F | In vivo inhibition of ACLY in po dosed dog assessed as reduction in plasma cholesterol level after 15 days relative to control | Canis lupus familiaris | 1 | ALA4270641 | organism-based format | Scientific Literature | |
17. | ALA4275785 | F | In vivo inhibition of ACLY in po dosed dog assessed as reduction in plasma triglyceride level after 15 days relative to control | Canis lupus familiaris | 1 | ALA4270641 | organism-based format | Scientific Literature |