# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3636864 | B | Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assay | Homo sapiens | 27 | ALA3632552 | single protein format | Scientific Literature | |
2. | ALA3636865 | B | Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assay | Homo sapiens | 27 | ALA3632552 | single protein format | Scientific Literature | |
3. | ALA3636866 | B | Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assay | Homo sapiens | 27 | ALA3632552 | single protein format | Scientific Literature | |
4. | ALA3636867 | B | Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assay | Mus musculus | 27 | ALA3632552 | single protein format | Scientific Literature | |
5. | ALA3636870 | B | Inhibition of mouse NaV1.1 by IonWorks quattro automated electrophysiology assay | Mus musculus | 6 | ALA3632552 | single protein format | Scientific Literature | |
6. | ALA3636871 | A | Fraction unbound in mouse plasma | Mus musculus | 6 | ALA3632552 | cell-free format | Scientific Literature | |
7. | ALA3636873 | A | Tmax in db/db mouse at 30 mg/kg, po | Mus musculus | 2 | ALA3632552 | organism-based format | Scientific Literature | |
8. | ALA3636875 | A | Cmax in db/db mouse at 30 mg/kg, po | Mus musculus | 2 | ALA3632552 | organism-based format | Scientific Literature | |
9. | ALA3636877 | A | AUC in db/db mouse at 30 mg/kg, po | Mus musculus | 2 | ALA3632552 | organism-based format | Scientific Literature | |
10. | ALA3636879 | F | Analgesic activity in mouse assessed as inhibition of acetic acid-induced writhing response | Mus musculus | 6 | ALA3632552 | organism-based format | Scientific Literature | |
11. | ALA3636880 | T | Toxicity in po dosed mouse assessed as reduction of locomotor activity | Mus musculus | 6 | ALA3632552 | organism-based format | Scientific Literature | |
12. | ALA3636881 | A | Therapeutic index, ratio of toxic ID50 in mouse to analgesic activity ED50 in mouse | Mus musculus | 3 | ALA3632552 | organism-based format | Scientific Literature |