| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3637515 | Binding | Inhibition of human recombinant renin preincubated for 30 mins followed by substrate addition measured after 15 mins by fluorescence analysis | Homo sapiens | 44 | ALA3632546 | single protein format | Scientific Literature | |
| 2. | ALA3637516 | Binding | Inhibition of human recombinant cathepsin D preincubated for 30 mins followed by substrate addition measured after 15 mins by fluorescence analysis | Homo sapiens | 1 | ALA3632546 | single protein format | Scientific Literature | |
| 3. | ALA3637517 | Binding | Inhibition of human recombinant cathepsin E preincubated for 30 mins followed by substrate addition measured after 15 mins by fluorescence analysis | Homo sapiens | 1 | ALA3632546 | single protein format | Scientific Literature | |
| 4. | ALA3637518 | Functional | Antihypersensitive activity in po dosed double transgenic hypertensive mouse harboring human angiotensinogen and human renin genes assessed as reduction of mean arterial blood pressure monitored 24 hrs post dose | Mus musculus | 1 | ALA3632546 | organism-based format | Scientific Literature | |
| 5. | ALA3637519 | Functional | Antihypersensitive activity in po dosed double transgenic hypertensive mouse harboring human angiotensinogen and human renin genes assessed as maximum reduction of mean arterial blood pressure monitored 24 hrs post dose | Mus musculus | 1 | ALA3632546 | organism-based format | Scientific Literature | |
| 6. | ALA3637520 | Functional | Antihypersensitive activity in po dosed double transgenic hypertensive mouse harboring human angiotensinogen and human renin genes assessed as time duration for sustained reduction of mean arterial blood pressure monitored 24 hrs post dose | Mus musculus | 1 | ALA3632546 | organism-based format | Scientific Literature | |
| 7. | ALA3637521 | Functional | Antihypersensitive activity in double transgenic hypertensive mouse harboring human angiotensinogen and human renin genes assessed as reduction of mean arterial blood pressure at 8.5 umol/kg, po monitored 24 hrs post dose | Mus musculus | 2 | ALA3632546 | organism-based format | Scientific Literature | |
| 8. | ALA3637522 | Functional | Antihypersensitive activity in double transgenic hypertensive mouse harboring human angiotensinogen and human renin genes assessed as reduction of mean arterial blood pressure at 17 to 34 umol/kg, po monitored 24 hrs post dose | Mus musculus | 1 | ALA3632546 | organism-based format | Scientific Literature |
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