#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3635655	F	Cytotoxicity against human NCI-H1975 cells harboring EGFR L858R/T790M double mutant assessed as inhibition of cell proliferation after 72 hrs by CellTiter-Glo assay	Homo sapiens	13		cell-based format	Scientific Literature
2.	ALA3635656	F	Cytotoxicity against human HCC827 cells harboring EGFR 746 to 750 deletion mutant assessed as inhibition of cell proliferation after 72 hrs by CellTiter-Glo assay	Homo sapiens	12		cell-based format	Scientific Literature
3.	ALA3635657	A	Cytotoxicity against human A431 cells expressing wild-type EGFR assessed as inhibition of cell proliferation after 72 hrs by CellTiter-Glo assay	Homo sapiens	13		cell-based format	Scientific Literature
4.	ALA3635658	B	Inhibition of EGFR L858R/T790M double mutant phosphorylation in human NCI-H1975 cells after 60 mins by mesoscale multiplex assay	Homo sapiens	5		cell-based format	Scientific Literature
5.	ALA3635659	B	Inhibition of EGFR 746 to 750 deletion mutant phosphorylation in human HCC827 cells after 60 mins by mesoscale multiplex assay	Homo sapiens	5		cell-based format	Scientific Literature
6.	ALA3635803	A	Inhibition of wild type EGFR phosphorylation in human A431 cells after 60 mins by mesoscale multiplex assay	Homo sapiens	5		cell-based format	Scientific Literature
7.	ALA3635804	A	Selectivity ratio of IC50 for wild type EGFR phosphorylation in human A431 cells to IC50 for EGFR L858R/T790M double mutant phosphorylation in human NCI-H1975 cells	Homo sapiens	3		cell-based format	Scientific Literature
8.	ALA3635805	A	Selectivity ratio of IC50 for wild type EGFR phosphorylation in human A431 cells to IC50 for EGFR 746 to 750 deletion mutant phosphorylation in human HCC827 cells	Homo sapiens	3		cell-based format	Scientific Literature
9.	ALA3635806	A	Selectivity ratio of IC50 for human A431 cells expressing wild-type EGFR to IC50 for human NCI-H1975 cells harboring EGFR L858R/T790M double mutant	Homo sapiens	1		cell-based format	Scientific Literature
10.	ALA3635807	A	Selectivity ratio of IC50 for human A431 cells expressing wild-type EGFR to IC50 for human HCC827 cells harboring EGFR 746 to 750 deletion mutant	Homo sapiens	1		cell-based format	Scientific Literature
11.	ALA3635808	F	In vivo inhibition of EGFR L858R/T790M double mutant phosphorylation in human NCI-H1975 cells xenografted in athymic nude mouse at 30 mg/kg, po measured at 4 hrs by mesoscale multiplex assay relative to control	Mus musculus	9		organism-based format	Scientific Literature
12.	ALA3635809	F	Antitumor activity against human NCI-H1975 cells xenografted in athymic nude mouse assessed as tumor growth inhibition at 30 mg/kg, po qd administered for 2 weeks started on day 6 post tumor implantation measured on day 19 relative to control	Homo sapiens	3		organism-based format	Scientific Literature
13.	ALA3635810	A	Hepatobiliary toxicity in Sprague-Dawley rat measured for 4 days	Rattus norvegicus	3		organism-based format	Scientific Literature
14.	ALA3635811	A	Clearance in Sprague-Dawley rat at 1 mg/kg, iv	Rattus norvegicus	4		organism-based format	Scientific Literature
15.	ALA3635812	A	Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv	Rattus norvegicus	4		organism-based format	Scientific Literature
16.	ALA3635813	A	Half life in Sprague-Dawley rat at 1 mg/kg, iv	Rattus norvegicus	4		organism-based format	Scientific Literature
17.	ALA3635814	A	AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, po	Rattus norvegicus	4		organism-based format	Scientific Literature
18.	ALA3635815	A	Oral bioavailability in Sprague-Dawley rat at 10 mg/kg	Rattus norvegicus	4		organism-based format	Scientific Literature
19.	ALA3755796	A	Inhibiton of wild type EGFR (unknown origin) using Poly (Glu4Tyr1) as substrate incubated for 1 hr by ELISA	Homo sapiens	25		single protein format	Scientific Literature
20.	ALA3755797	B	Inhibition of EGFR L858R/T790M mutant (unknown origin) using Poly(Glu,Tyr)4:1 as substrate incubated for 1 hr by ELISA	Homo sapiens	25		protein format	Scientific Literature