| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3635132 | F | Agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as calcium mobilization at 0.3 uM by FLIPR assay | Homo sapiens | 7 | ALA3632469 | cell-based format | Scientific Literature | |
| 2. | ALA3635133 | F | Agonist activity at human muscarinic M2 acetylcholine receptor expressed in CHO cells co-expressing Galpha16 assessed as calcium mobilization at 0.3 uM by FLIPR assay | Homo sapiens | 7 | ALA3632469 | cell-based format | Scientific Literature | |
| 3. | ALA3635134 | F | Agonist activity at human muscarinic M3 acetylcholine receptor expressed in CHO cells assessed as calcium mobilization at 0.3 uM by FLIPR assay | Homo sapiens | 7 | ALA3632469 | cell-based format | Scientific Literature | |
| 4. | ALA3635135 | F | Partial agonist activity at human muscarinic M4 acetylcholine receptor expressed in CHO cells co-expressing Galpha16 assessed as calcium mobilization at 0.3 uM by FLIPR assay | Homo sapiens | 7 | ALA3632469 | cell-based format | Scientific Literature | |
| 5. | ALA3635137 | F | Partial agonist activity at human muscarinic M4 acetylcholine receptor expressed in CHO cells co-expressing Galpha16 assessed as calcium mobilization at 30 uM by FLIPR assay | Homo sapiens | 2 | ALA3632469 | cell-based format | Scientific Literature | |
| 6. | ALA3635138 | F | Agonist activity at human muscarinic M5 acetylcholine receptor expressed in CHO cells assessed as calcium mobilization at 30 uM by FLIPR assay | Homo sapiens | 2 | ALA3632469 | cell-based format | Scientific Literature | |
| 7. | ALA3635139 | P | Permeability of the compound at pH 7.4 by PAMPA method | 1 | ALA3632469 | small-molecule physicochemical format | Scientific Literature | ||
| 8. | ALA3635140 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 1 | ALA3632469 | single protein format | Scientific Literature | |
| 9. | ALA3635141 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | ALA3632469 | single protein format | Scientific Literature | |
| 10. | ALA3635142 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 1 | ALA3632469 | single protein format | Scientific Literature | |
| 11. | ALA3635143 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | ALA3632469 | single protein format | Scientific Literature | |
| 12. | ALA3635144 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | ALA3632469 | single protein format | Scientific Literature | |
| 13. | ALA3635145 | A | Induction of human AhR | Homo sapiens | 1 | ALA3632469 | single protein format | Scientific Literature | |
| 14. | ALA3635146 | A | Induction of human PXR | Homo sapiens | 1 | ALA3632469 | single protein format | Scientific Literature | |
| 15. | ALA3635147 | A | Binding affinity to p-glycoprotein (unknown origin) assessed as efflux ratio by cell based assay | Homo sapiens | 1 | ALA3632469 | cell-based format | Scientific Literature | |
| 16. | ALA3635148 | A | Ratio of drug level in brain to blood in rat | Rattus norvegicus | 1 | ALA3632469 | tissue-based format | Scientific Literature | |
| 17. | ALA3635149 | B | Binding affinity to adrenergic alpha1A receptor (unknown origin) at 3 uM by radioligand-binding assay | Homo sapiens | 1 | ALA3632469 | single protein format | Scientific Literature | |
| 18. | ALA3635150 | B | Binding affinity to dopamine D2 receptor (unknown origin) at 3 uM by radioligand-binding assay | Homo sapiens | 1 | ALA3632469 | single protein format | Scientific Literature | |
| 19. | ALA3635151 | B | Binding affinity to histamine H1 receptor (unknown origin) at 3 uM by radioligand-binding assay | Homo sapiens | 1 | ALA3632469 | single protein format | Scientific Literature | |
| 20. | ALA3635152 | F | Agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as calcium mobilization by FLIPR assay | Homo sapiens | 1 | ALA3632469 | cell-based format | Scientific Literature |
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