| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3637534 | Binding | Inhibition of human carbonic anhydrase 1 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay | Homo sapiens | 17 | ALA3632486 | single protein format | Scientific Literature | |
| 2. | ALA3637535 | Binding | Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay | Homo sapiens | 11 | ALA3632486 | single protein format | Scientific Literature | |
| 3. | ALA3635395 | Binding | Inhibition of human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assay | Homo sapiens | 17 | ALA3632486 | single protein format | Scientific Literature | |
| 4. | ALA4383292 | Binding | Inhibition of Enterococcus faecalis JH2-2 C-terminal 6His-tagged DdlB expressed in Escherichia coli LMG194 preincubated for 30 mins followed by substrate addition and measured after 20 mins by Biomol Green reagent assay | Enterococcus faecalis | 22 | ALA4382202 | assay format | Scientific Literature | |
| 5. | ALA4383293 | Binding | Inhibition of Enterococcus faecalis JH2-2 C-terminal 6His-tagged DdlB expressed in Escherichia coli LMG194 at 10 uM preincubated for 30 mins followed by substrate addition and measured after 20 mins by Biomol Green reagent assay relative to control | Enterococcus faecalis | 24 | ALA4382202 | assay format | Scientific Literature | |
| 6. | ALA4383295 | Binding | Inhibition of Enterococcus faecalis JH2-2 C-terminal 6His-tagged DdlB expressed in Escherichia coli LMG194 at IC50 after 10 mins by Biomol Green reagent assay relative to control | Enterococcus faecalis | 1 | ALA4382202 | assay format | Scientific Literature | |
| 7. | ALA4383296 | Binding | Inhibition of Enterococcus faecalis JH2-2 C-terminal 6His-tagged DdlB expressed in Escherichia coli LMG194 at IC50 after 90 mins by Biomol Green reagent assay relative to control | Enterococcus faecalis | 1 | ALA4382202 | assay format | Scientific Literature | |
| 8. | ALA4383297 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 to 24 hrs by microdilution assay | Staphylococcus aureus | 42 | ALA4382202 | organism-based format | Scientific Literature | |
| 9. | ALA4383298 | Functional | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 18 to 24 hrs by microdilution assay | Enterococcus faecalis | 42 | ALA4382202 | organism-based format | Scientific Literature | |
| 10. | ALA4383299 | Functional | Antibacterial activity against vancomycin-resistant Enterococcus faecalis BM 4390 after 18 to 24 hrs by microdilution assay | Enterococcus faecalis | 26 | ALA4382202 | organism-based format | Scientific Literature | |
| 11. | ALA4383300 | Functional | Antibacterial activity against vancomycin-resistant Enterococcus faecalis JH2-2::C1 after 18 to 24 hrs by microdilution assay | Enterococcus faecalis | 26 | ALA4382202 | organism-based format | Scientific Literature | |
| 12. | ALA4383301 | Functional | Antibacterial activity against vancomycin-resistant Enterococcus faecalis BM 4575 clinical isolate after 18 to 24 hrs by microdilution assay | Enterococcus faecalis | 26 | ALA4382202 | organism-based format | Scientific Literature | |
| 13. | ALA4383302 | Functional | Antibacterial activity against methicillin and vancomycin intermediate resistant Staphylococcus aureus MU50 after 18 to 24 hrs by microdilution assay | Staphylococcus aureus | 26 | ALA4382202 | organism-based format | Scientific Literature | |
| 14. | ALA4383303 | Functional | Antibacterial activity against methicillin and linezolid resistant Staphylococcus aureus NRS 119 clinical isolate after 18 to 24 hrs by microdilution assay | Staphylococcus aureus | 26 | ALA4382202 | organism-based format | Scientific Literature | |
| 15. | ALA4383304 | Functional | Antibacterial activity against community-acquired methicillin and erythromycin resistant Staphylococcus aureus SA 325 after 18 to 24 hrs by microdilution assay | Staphylococcus aureus | 26 | ALA4382202 | organism-based format | Scientific Literature | |
| 16. | ALA4383305 | Functional | Antibacterial activity against hospital-acquired methicillin/ciprofloxacin/moxifloxacin resistant Staphylococcus aureus SA 481 after 18 to 24 hrs by microdilution assay | Staphylococcus aureus | 26 | ALA4382202 | organism-based format | Scientific Literature | |
| 17. | ALA4383306 | Functional | Antibacterial activity against hospital-acquired methicillin and vacomycin resistant Staphylococcus aureus VRS-1 after 18 to 24 hrs by microdilution assay | Staphylococcus aureus | 26 | ALA4382202 | organism-based format | Scientific Literature | |
| 18. | ALA4383356 | Binding | Inhibition of Enterococcus faecalis JH2-2 C-terminal 6His-tagged DdlB expressed in Escherichia coli LMG194 preincubated for 30 mins followed by substrate addition and measured after 20 mins in presence of 0.01% Triton X-100 by Biomol Green reagent assay | Enterococcus faecalis | 1 | ALA4382202 | assay format | Scientific Literature | |
| 19. | ALA4687405 | Binding | Inhibition of recombinant Enterococcus faecalis C-terminal His6-tagged DdlB expressed in Escherichia coli LMG194 using D-Ala as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured after 20 mins by malachite green based colorimetric analysis | Enterococcus faecalis | 15 | ALA4680268 | assay format | Scientific Literature | |
| 20. | ALA4687406 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as reduction in bacterial growth incubated for 18 to 24 hrs by broth microdilution method | Staphylococcus aureus | 31 | ALA4680268 | organism-based format | Scientific Literature |
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