# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3636446 | B | Inhibition of cyclin E phosphorylation in HEK293T cells at 100 uM after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA3632525 | cell-based format | Scientific Literature | |
2. | ALA3636447 | B | Inhibition of CDK2/Cyclin E in African green monkey Vero cells assessed as reduction of hyperphosphorylated pRB expression at 100 uM after 24 hrs by Western blot analysis relative to control | Chlorocebus sabaeus | 1 | ALA3632525 | cell-based format | Scientific Literature | |
3. | ALA3636448 | B | Inhibition of CDK2/Cyclin E in human Hep2 cells assessed as reduction of hyperphosphorylated pRB expression at 100 uM after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA3632525 | cell-based format | Scientific Literature | |
4. | ALA3636449 | B | Inhibition of CDK2/Cyclin E in HEK293T cells assessed as reduction of hyperphosphorylated pRB expression at 100 uM after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA3632525 | cell-based format | Scientific Literature | |
5. | ALA3636450 | B | Inhibition of CDK2/Cyclin E in HEK293T cells assessed as reduction of EGF-stimulated E2F pathway after 24 hrs by dual-Glo luciferase reporter gene assay relative to control | Homo sapiens | 1 | ALA3632525 | cell-based format | Scientific Literature | |
6. | ALA3636451 | B | Binding affinity to CDK2 allosteric site (unknown origin) | Homo sapiens | 2 | ALA3632525 | single protein format | Scientific Literature | |
7. | ALA3636415 | A | Cytotoxicity against African green monkey Vero cells assessed as reduction of cell viability at 80 to 100 uM by CellTiter-Glo luminescent assay | Chlorocebus sabaeus | 1 | ALA3632525 | cell-based format | Scientific Literature | |
8. | ALA3636416 | F | Cytotoxicity against human Hep2 cells assessed as reduction of cell viability at 80 to 100 uM by CellTiter-Glo luminescent assay | Homo sapiens | 1 | ALA3632525 | cell-based format | Scientific Literature | |
9. | ALA3636417 | F | Cytotoxicity against HEK293T cells assessed as reduction of cell viability at 80 to 100 uM by CellTiter-Glo luminescent assay | Homo sapiens | 1 | ALA3632525 | cell-based format | Scientific Literature | |
10. | ALA3636418 | A | Cytotoxicity against African green monkey Vero cells assessed as reduction of cell viability after 24 to 72 hrs by CellTiter-Glo luminescent assay | Chlorocebus sabaeus | 1 | ALA3632525 | cell-based format | Scientific Literature | |
11. | ALA3636419 | F | Cytotoxicity against human Hep2 cells assessed as reduction of cell viability after 24 to 72 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 1 | ALA3632525 | cell-based format | Scientific Literature | |
12. | ALA3636420 | F | Cytotoxicity against HEK293T cells assessed as reduction of cell viability after 24 to 72 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 1 | ALA3632525 | cell-based format | Scientific Literature | |
13. | ALA3636421 | B | Inhibition of CDK2 phosphorylation in African green monkey Vero cells at 100 uM after 24 hrs by Western blot analysis relative to control | Chlorocebus sabaeus | 1 | ALA3632525 | cell-based format | Scientific Literature | |
14. | ALA3636422 | B | Inhibition of CDK2 phosphorylation in human Hep2 cells at 100 uM after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA3632525 | cell-based format | Scientific Literature | |
15. | ALA3636423 | B | Inhibition of CDK2 phosphorylation in HEK293T cells at 100 uM after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA3632525 | cell-based format | Scientific Literature | |
16. | ALA3636424 | B | Inhibition of cyclin E phosphorylation in African green monkey Vero cells at 100 uM after 24 hrs by Western blot analysis relative to control | Chlorocebus sabaeus | 1 | ALA3632525 | cell-based format | Scientific Literature | |
17. | ALA3636425 | B | Inhibition of cyclin E phosphorylation in human Hep2 cells at 100 uM after 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA3632525 | cell-based format | Scientific Literature |