# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3636173 | F | Antiproliferative activity against human GBM1 cells assessed as reduction in cell viability at 10 uM incubated for 72 hrs by WST-1 method | Homo sapiens | 24 | ALA3632488 | cell-based format | Scientific Literature | |
2. | ALA3636174 | F | Antiproliferative activity against human GBM2 cells assessed as reduction in cell viability at 10 uM incubated for 72 hrs by WST-1 method | Homo sapiens | 24 | ALA3632488 | cell-based format | Scientific Literature | |
3. | ALA3636175 | F | Antiproliferative activity against human GBM1 cells assessed as reduction in cell viability incubated for 72 hrs by WST-1 method | Homo sapiens | 24 | ALA3632488 | cell-based format | Scientific Literature | |
4. | ALA3636176 | F | Antiproliferative activity against human GBM2 cells assessed as reduction in cell viability incubated for 72 hrs by WST-1 method | Homo sapiens | 24 | ALA3632488 | cell-based format | Scientific Literature | |
5. | ALA3636177 | A | Cytotoxicity against normal human astrocytes assessed as cell viability incubated for 72 hrs by WST-1 method | Homo sapiens | 24 | ALA3632488 | cell-based format | Scientific Literature | |
6. | ALA3636178 | U | Selectivity index, ratio of IC50 for normal human astrocytes to IC50 for human GBM1 cells | Homo sapiens | 24 | ALA3632488 | cell-based format | Scientific Literature | |
7. | ALA3636179 | U | Selectivity index, ratio of IC50 for normal human astrocytes to IC50 for human GBM2 cells | Homo sapiens | 24 | ALA3632488 | cell-based format | Scientific Literature | |
8. | ALA3636180 | F | Antiproliferative activity against human GBM3 cells assessed as reduction in cell viability at 10 uM incubated for 72 hrs by WST-1 method | Homo sapiens | 24 | ALA3632488 | cell-based format | Scientific Literature | |
9. | ALA3636674 | F | Antiproliferative activity against human GBM3 cells assessed as reduction in cell viability incubated for 72 hrs by WST-1 method | Homo sapiens | 24 | ALA3632488 | cell-based format | Scientific Literature | |
10. | ALA3636675 | U | Selectivity index, ratio of IC50 for normal human astrocytes to IC50 for human GBM3 cells | Homo sapiens | 24 | ALA3632488 | cell-based format | Scientific Literature | |
11. | ALA3636676 | F | Induction of apoptosis in human GBM1 cells assessed as loss of mitochondrial membrane potential at 10 uM after 2 hrs by JC-1 staining based fluorescence microscopy | Homo sapiens | 6 | ALA3632488 | cell-based format | Scientific Literature | |
12. | ALA3636677 | F | Induction of apoptosis in human GBM2 cells assessed as loss of mitochondrial membrane potential at 10 uM after 2 hrs by JC-1 staining based fluorescence microscopy | Homo sapiens | 1 | ALA3632488 | cell-based format | Scientific Literature | |
13. | ALA3636678 | F | Induction of apoptosis in human GBM2 cells assessed as loss of mitochondrial membrane potential in presence of cyclosporine A at 10 uM after 2 hrs by JC-1 staining based fluorescence microscopy | Homo sapiens | 1 | ALA3632488 | cell-based format | Scientific Literature | |
14. | ALA3636679 | F | Induction of apoptosis in human GBM2 cells assessed as loss of mitochondrial membrane potential in presence of BAPTA at 10 uM after 2 hrs by JC-1 staining based fluorescence microscopy | Homo sapiens | 1 | ALA3632488 | cell-based format | Scientific Literature | |
15. | ALA3636680 | B | Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane at 10 uM by radiometric competitive assay | Rattus norvegicus | 6 | ALA3632488 | tissue-based format | Scientific Literature | |
16. | ALA3636681 | B | Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane at 1 uM by radiometric competitive assay | Rattus norvegicus | 7 | ALA3632488 | tissue-based format | Scientific Literature | |
17. | ALA3636682 | B | Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane at 100 nM by radiometric competitive assay | Rattus norvegicus | 7 | ALA3632488 | tissue-based format | Scientific Literature | |
18. | ALA3636683 | B | Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane at 10 nM by radiometric competitive assay | Rattus norvegicus | 7 | ALA3632488 | tissue-based format | Scientific Literature | |
19. | ALA3636685 | B | Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assay | Rattus norvegicus | 7 | ALA3632488 | tissue-based format | Scientific Literature | |
20. | ALA3636847 | F | Tumoricidal effect in patient derived GBM 464T cells assessed as reduction in neurosphere formation at 0.1 uM after 1 to 2 weeks by 3D tumor clonogenic assay | Homo sapiens | 1 | ALA3632488 | cell-based format | Scientific Literature |