# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3636077 | B | Inhibition of recombinant Brugia malayi TMK using dTMP as substrate by pyruvate kinase/lactate dehydrogenase coupled assay | Brugia malayi | 15 | assay format | Scientific Literature | ||
2. | ALA3636078 | F | Antifilarial activity against adult Brugia malayi assessed as motility reduction after 1 hr by microscopic analysis | Brugia malayi | 3 | organism-based format | Scientific Literature | ||
3. | ALA3636079 | F | Antifilarial activity against Brugia malayi microfilariae assessed as motility reduction after 1 hr by microscopic analysis | Brugia malayi | 3 | organism-based format | Scientific Literature | ||
4. | ALA3636080 | A | Cytotoxicity against African green monkey Vero cells after 72 hrs by resazurin dye-based fluorometric analysis | Chlorocebus sabaeus | 3 | cell-based format | Scientific Literature | ||
5. | ALA3636081 | A | Therapeutic index, ratio of CC50 for monkey VERO cells to IC50 for adult Brugia malayi | 3 | cell-based format | Scientific Literature | |||
6. | ALA3636082 | A | Therapeutic index, ratio of CC50 for monkey VERO cells to IC50 for Brugia malayi microfilariae | 3 | cell-based format | Scientific Literature | |||
7. | ALA3636083 | F | Antifilarial activity against adult Brugia malayi assessed as reduction in viability at 10 uM/ml after 24 to 48 hrs by MTT assay | Brugia malayi | 2 | organism-based format | Scientific Literature | ||
8. | ALA3636084 | F | Antifilarial activity against adult Brugia malayi assessed as reduction in viability at 5 uM/ml after 24 to 48 hrs by MTT assay | Brugia malayi | 3 | organism-based format | Scientific Literature | ||
9. | ALA3636085 | F | Antifilarial activity against adult Brugia malayi assessed as reduction in viability at 2.5 uM/ml after 24 to 48 hrs by MTT assay | Brugia malayi | 3 | organism-based format | Scientific Literature | ||
10. | ALA3636086 | F | Antifilarial activity against adult Brugia malayi assessed as reduction in viability at 1.25 uM/ml after 24 to 48 hrs by MTT assay | Brugia malayi | 3 | organism-based format | Scientific Literature | ||
11. | ALA3636091 | F | Antifilarial activity against adult Brugia malayi assessed as motility reduction at 10 uM/ml after 1 hr by microscopic analysis | Brugia malayi | 2 | organism-based format | Scientific Literature | ||
12. | ALA3636092 | F | Antifilarial activity against adult Brugia malayi assessed as motility reduction at 5 uM/ml after 1 hr by microscopic analysis | Brugia malayi | 3 | organism-based format | Scientific Literature | ||
13. | ALA3636093 | F | Antifilarial activity against adult Brugia malayi assessed as motility reduction at 2.5 uM/ml after 1 hr by microscopic analysis | Brugia malayi | 3 | organism-based format | Scientific Literature | ||
14. | ALA3636094 | F | Antifilarial activity against adult Brugia malayi assessed as motility reduction at 1.25 uM/ml after 1 hr by microscopic analysis | Brugia malayi | 3 | organism-based format | Scientific Literature | ||
15. | ALA3636203 | F | Antifilarial activity against Brugia malayi microfilariae assessed as motility reduction at 10 uM/ml after 1 hr by microscopic analysis | Brugia malayi | 2 | organism-based format | Scientific Literature | ||
16. | ALA3636204 | F | Antifilarial activity against Brugia malayi microfilariae assessed as motility reduction at 5 uM/ml after 1 hr by microscopic analysis | Brugia malayi | 3 | organism-based format | Scientific Literature | ||
17. | ALA3636205 | F | Antifilarial activity against Brugia malayi microfilariae assessed as motility reduction at 2.5 uM/ml after 1 hr by microscopic analysis | Brugia malayi | 3 | organism-based format | Scientific Literature | ||
18. | ALA3636702 | F | Antifilarial activity against Brugia malayi microfilariae assessed as motility reduction at 1.25 uM/ml after 1 hr by microscopic analysis | Brugia malayi | 3 | organism-based format | Scientific Literature |