# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3637317 | B | Inhibition of ACAT in human MDM cells assessed as inhibition of foam cell formation by measuring acetylated LDL-induced [3H]cholesterol ester accumulation at 5 uM after 24 hrs in presence of 0.1 mM [3H]oleate | Homo sapiens | 8 | ALA3632472 | cell-based format | Scientific Literature | |
2. | ALA3637318 | A | Cytotoxicity against human MDM cells at 5 uM after 24 hrs | Homo sapiens | 8 | ALA3632472 | cell-based format | Scientific Literature | |
3. | ALA3637319 | B | Inhibition of human ACAT1 expressed in CHO cells assessed as inhibition of [3H]cholesterol ester accumulation at 5 uM in presence of 0.1 mM [3H]oleate-conjugated BSA | Homo sapiens | 8 | ALA3632472 | cell-based format | Scientific Literature | |
4. | ALA3637434 | B | Inhibition of human ACAT2 expressed in CHO cells assessed as inhibition of [3H]cholesterol ester accumulation at 5 uM in presence of 0.1 mM [3H]oleate-conjugated BSA | Homo sapiens | 8 | ALA3632472 | cell-based format | Scientific Literature | |
5. | ALA3637444 | B | Inhibition of human ACAT1 expressed in CHO cells at 5 uM using [14C]oleoyl-CoA as substrate | Homo sapiens | 4 | ALA3632472 | cell-based format | Scientific Literature | |
6. | ALA3637445 | B | Inhibition of human ACAT2 expressed in CHO cells at 5 uM using [14C]oleoyl-CoA as substrate | Homo sapiens | 4 | ALA3632472 | cell-based format | Scientific Literature |