# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3636719 | B | Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated TNF-alpha production at 5 to 10 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis | Mus musculus | 1 | ALA3632615 | cell-based format | Scientific Literature | |
2. | ALA3636720 | B | Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated TNF-alpha production at 0.5 to 5 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis in presence of cordycepin | Mus musculus | 2 | ALA3632615 | cell-based format | Scientific Literature | |
3. | ALA3636721 | B | Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated TNF-alpha production at 0.5 to 5 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis in presence of adenosine | Mus musculus | 2 | ALA3632615 | cell-based format | Scientific Literature | |
4. | ALA3636884 | B | Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated PGE2 production at 2.5 to 10 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis | Mus musculus | 2 | ALA3632615 | cell-based format | Scientific Literature | |
5. | ALA3636885 | B | Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated PGE2 production at 0.5 to 5 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis in presence of cordycepin | Mus musculus | 2 | ALA3632615 | cell-based format | Scientific Literature | |
6. | ALA3636886 | B | Inhibition of TLR4-mediated NF-kappaB signaling pathway in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-stimulated PGE2 production at 0.5 to 5 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis in presence of adenosine | Mus musculus | 2 | ALA3632615 | cell-based format | Scientific Literature | |
7. | ALA3636888 | B | Inhibition of TLR4 in LPS-stimulated BALB/c mouse RAW264.7 cells at 10 to 50 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis | Mus musculus | 1 | ALA3632615 | cell-based format | Scientific Literature | |
8. | ALA3636889 | B | Inhibition of TLR4 in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-induced IkappaB-alpha phosphorylation at 10 to 50 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis | Mus musculus | 1 | ALA3632615 | cell-based format | Scientific Literature | |
9. | ALA3636890 | B | Inhibition of TLR4 in BALB/c mouse RAW264.7 cells assessed as suppression of LPS-induced COX2 expression at 10 to 50 ug/ml preincubated for 1 hr followed by LPS challenge measured after 6 hrs by immunoblot analysis | Mus musculus | 1 | ALA3632615 | cell-based format | Scientific Literature |