# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3635513 | B | Inhibition of rat PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 mins by scintillation proximity assay | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
2. | ALA3635514 | B | Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 mins by scintillation proximity assay | Homo sapiens | 46 | single protein format | Scientific Literature | ||
3. | ALA3635517 | B | Inhibition of mouse PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 mins by scintillation proximity assay | Mus musculus | 1 | single protein format | Scientific Literature | ||
4. | ALA3635518 | B | Inhibition of recombinant human PDE1A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP at 1 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
5. | ALA3635519 | B | Inhibition of recombinant human PDE4D using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP at 1 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
6. | ALA3635520 | B | Inhibition of recombinant human PDE7A assessed as hydrolysis of [3H]cAMP to [3H]AMP at 1 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
7. | ALA3635521 | B | Inhibition of recombinant human PDE8A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP at 1 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
8. | ALA3635522 | B | Inhibition of recombinant human PDE11A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of cAMP to AMP at 1 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
9. | ALA3635523 | B | Inhibition of recombinant human PDE1A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP at 10 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
10. | ALA3635524 | B | Inhibition of recombinant human PDE4D using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP at 10 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
11. | ALA3635525 | B | Inhibition of recombinant human PDE7A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP at 10 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
12. | ALA3635526 | B | Inhibition of recombinant human PDE8A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP at 10 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
13. | ALA3635527 | B | Inhibition of recombinant human PDE11A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP at 10 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
14. | ALA3635528 | B | Inhibition of recombinant human PDE2A using cAMP as substrate at 1 uM after 30 mins by HTRF assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
15. | ALA3635529 | B | Inhibition of recombinant human PDE3A using cAMP as substrate at 1 uM after 30 mins by HTRF assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
16. | ALA3635530 | B | Inhibition of recombinant human PDE2A using cAMP as substrate at 10 uM after 30 mins by HTRF assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
17. | ALA3635531 | B | Inhibition of recombinant human PDE3A using cAMP as substrate at 10 uM after 30 mins by HTRF assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
18. | ALA3635532 | B | Inhibition of recombinant human PDE5A using [3H]cGMP/cGMP as substrate assessed as hydrolysis of [3H]cGMP to [3H]GMP at 1 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
19. | ALA3635533 | B | Inhibition of recombinant human PDE9A using [3H]cGMP/cGMP as substrate assessed as hydrolysis of [3H]cGMP to [3H]GMP at 1 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
20. | ALA3635534 | B | Inhibition of recombinant human PDE5A using [3H]cGMP/cGMP as substrate assessed as hydrolysis of [3H]cGMP to [3H]GMP at 10 uM after 30 mins by scintillation proximity assay | Homo sapiens | 9 | single protein format | Scientific Literature |