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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA3635512 ADME AUC (0 to 24 hrs) in Beagle dog assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 1.1 mg/kg, iv Canis lupus familiaris 1 ALA3632475 organism-based format Scientific Literature 2. ALA3636184 ADME Cmax in Sprague Dawley rat assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 11.04 mg/kg, po measured up to 8 hrs Rattus norvegicus 2 ALA3632475 organism-based format Scientific Literature 3. ALA3636185 ADME Tmax in Sprague Dawley rat assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 11.04 mg/kg, po measured after 8hrs Rattus norvegicus 2 ALA3632475 organism-based format Scientific Literature 4. ALA3636186 ADME AUC (0 to t) in Sprague Dawley rat assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 11.04 mg/kg, po measured after 8hrs Rattus norvegicus 2 ALA3632475 organism-based format Scientific Literature 5. ALA3636193 ADME Cmax in Sprague Dawley rat assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 1.1 mg/kg, iv Rattus norvegicus 1 ALA3632475 organism-based format Scientific Literature 6. ALA3636194 ADME AUC (0 to 24 hrs) in Sprague Dawley rat assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 1.1 mg/kg, iv Rattus norvegicus 1 ALA3632475 organism-based format Scientific Literature 7. ALA3636195 ADME Clearance in Sprague Dawley rat assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 1.1 mg/kg, iv Rattus norvegicus 1 ALA3632475 organism-based format Scientific Literature 8. ALA3636196 ADME Cmax in Beagle dog assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 1.1 mg/kg, iv Canis lupus familiaris 1 ALA3632475 organism-based format Scientific Literature 9. ALA3636197 ADME Clearance in Beagle dog assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 1.1 mg/kg, iv Canis lupus familiaris 1 ALA3632475 organism-based format Scientific Literature 10. ALA3636198 ADME Cmax in Beagle dog assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 11.04 mg/kg, po Canis lupus familiaris 1 ALA3632475 organism-based format Scientific Literature 11. ALA3636199 ADME AUC (0 to 24 hrs) in Beagle dog assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 11.04 mg/kg, po Canis lupus familiaris 1 ALA3632475 organism-based format Scientific Literature 12. ALA3636309 ADME Clearance in Beagle dog assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 11.04 mg/kg, po Canis lupus familiaris 1 ALA3632475 organism-based format Scientific Literature 13. ALA3636310 ADME Tmax in Beagle dog assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 11.04 mg/kg, po Canis lupus familiaris 1 ALA3632475 organism-based format Scientific Literature 14. ALA3636311 ADME Cmax in cynomolgus monkey assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 1.1 mg/kg, iv Macaca fascicularis 1 ALA3632475 organism-based format Scientific Literature 15. ALA3636312 ADME AUC (0 to 24 hrs) in cynomolgus monkey assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 1.1 mg/kg, iv Macaca fascicularis 1 ALA3632475 organism-based format Scientific Literature 16. ALA3636313 ADME Clearance in cynomolgus monkey assessed as 6-(4-Fluorophenyl)-5-[4-quinolin-2-ylmethoxy)phenyl]-pyridine-2(1H)-one at 1.1 mg/kg, iv Macaca fascicularis 1 ALA3632475 organism-based format Scientific Literature 17. ALA3636314 Functional Antipsychotic activity in ip dosed CD1 mouse assessed as inhibition of 1 mg/kg apomorphine-induced climbing behavior administered 15 mins prior to apomorphine challenge measured every 5 mins for 1 hr Mus musculus 1 ALA3632475 organism-based format Scientific Literature 18. ALA3636315 Functional Antipsychotic activity in ip dosed CD1 mouse assessed as inhibition of 1 mg/kg apomorphine-induced sniffing behavior administered 15 mins prior to apomorphine challenge measured every 5 mins for 1 hr Mus musculus 1 ALA3632475 organism-based format Scientific Literature 19. ALA3636316 Functional Ratio of ED50 for sniffing behavior to ED50 for climbing behavior in ip dosed CD1 mouse Mus musculus 1 ALA3632475 organism-based format Scientific Literature 20. ALA3636317 Functional Antipsychotic activity in po dosed Sprague Dawley rat psychosis model assessed as inhibition of 0.2 mg/kg dizocilpine-induced hyperlocomotion administered 1 hr prior to dizocilpine challenge measured every 5 mins for 1 hr starting from the 15th min of post dizocilpine challenge Rattus norvegicus 1 ALA3632475 organism-based format Scientific Literature