| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3832785 | F | AntiTrypanosoma cruzi activity IC50 (uM) | Trypanosoma cruzi | 65 | organism-based format | MMV Pathogen Box | ||
| 2. | ALA3832786 | F | AntiTrypanosoma brucei activity T. b. brucei IC50 (uM) | Trypanosoma brucei | 64 | organism-based format | MMV Pathogen Box | ||
| 3. | ALA3832787 | F | AntiTrypanosoma brucei activity T. b. rhodesiense IC50 (uM) | Trypanosoma brucei | 62 | organism-based format | MMV Pathogen Box | ||
| 4. | ALA3832788 | F | AntiLeishmania activity L. major IC50 (uM) | Leishmania major | 6 | organism-based format | MMV Pathogen Box | ||
| 5. | ALA3832789 | F | AntiLeishmania activity L. infantum (macrophages) IC50 (uM) | Leishmania infantum | 65 | organism-based format | MMV Pathogen Box | ||
| 6. | ALA3832830 | F | Cytotoxicity data HepG2 CC20 (uM) | 172 | cell-based format | MMV Pathogen Box | |||
| 7. | ALA3832842 | F | MRC5 CC50 (uM) Cytotoxicity | 77 | cell-based format | MMV Pathogen Box | |||
| 8. | ALA3832843 | F | PMM CC50 (uM) Cytotoxicity | 65 | cell-based format | MMV Pathogen Box | |||
| 9. | ALA3987222 | B | Compound was evaluated for the inhibition of human FECH at 10uM | Homo sapiens | 400 | single protein format | MMV Pathogen Box | ||
| 10. | ALA3987223 | B | Compound was evaluated for the inhibition of human HMBS at 100uM | Homo sapiens | 400 | assay format | MMV Pathogen Box | ||
| 11. | ALA4140731 | F | Antiparasitic activity against Trypanosoma brucei brucei 427 after 48 hrs by PrestoBlue staining based fluorescence assay | Trypanosoma brucei brucei | 38 | organism-based format | Scientific Literature | ||
| 12. | ALA4140732 | F | Antiparasitic activity against Trypanosoma brucei brucei 427 assessed as parasitic growth inhibition at 5 uM after 48 hrs by PrestoBlue staining based fluorescence assay relative to control | Trypanosoma brucei brucei | 36 | organism-based format | Scientific Literature | ||
| 13. | ALA4140733 | P | Lipophilicity, log P of the compound | 36 | small-molecule physicochemical format | Scientific Literature | |||
| 14. | ALA4140734 | P | Aqueous solubility of the compound | 27 | small-molecule physicochemical format | Scientific Literature | |||
| 15. | ALA4140735 | A | Protein binding in human plasma | Homo sapiens | 27 | cell-free format | Scientific Literature | ||
| 16. | ALA4140736 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 27 | microsome format | Scientific Literature | ||
| 17. | ALA4140737 | A | Intrinsic clearance in rat hepatocytes assessed per 10'6 cells | Rattus norvegicus | 27 | cell-based format | Scientific Literature | ||
| 18. | ALA4140738 | F | Antiparasitic activity against Trypanosoma cruzi infected in mouse 3T3 cells assessed as growth inhibition after 96 hrs by beta-galactosidase reporter gene assay | Trypanosoma cruzi | 36 | organism-based format | Scientific Literature | ||
| 19. | ALA4140739 | F | Antiparasitic activity against Trypanosoma cruzi infected in mouse 3T3 cells assessed as growth inhibition at 10 uM after 96 hrs by beta-galactosidase reporter gene assay relative to control | Trypanosoma cruzi | 36 | organism-based format | Scientific Literature | ||
| 20. | ALA4140740 | F | Antiparasitic activity against Leishmania major amastigotes infected in mouse RAW 264.7 cells after 96 hrs by luciferase reporter gene assay | Leishmania major | 36 | organism-based format | Scientific Literature |
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