#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3705712	B	Inhibition Assay (Testosterone Hydroxylase): To gain insight into the selectivity of the synthetic compounds, nicotine, nicotine related alkaloids and nicotine metabolites for inhibition of other CYPs, we examined the major CYP present in human liver (i.e., CYP 3A4). That the CYP2A6 inhibitors showed low or no inhibitory activity against CYP3A4 suggests that the inhibitors examined selectively inhibited CYP2A6.	Homo sapiens	22	ALA3639082	assay format	BindingDB Database
2.	ALA3705713	B	Inhibition Assay: The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay (Greenlee et al., J Pharmacol Exp Ther, 1978). Our first studies were with highly purified human CYP2A6 that provided a convenient and relatively high-throughput measure of CYP2A6 inhibition.	Homo sapiens	89	ALA3639082	single protein format	BindingDB Database
3.	ALA4422401	B	Inhibition of human CYP2A6 expressed in insect cell microsomes assessed as reduction in enzyme-mediated coumarin 7-hydroxylation	Homo sapiens	111	ALA4421730	assay format	Patent Bioactivity Data
4.	ALA4422402	B	Selectivity index, ratio of IC50 for inhibition of human CYP3A4 assessed as reduction in enzyme-mediated testosterone 6-hydroxylation to IC50 for inhibition of human CYP2A6 assessed as reduction in enzyme-mediated coumarin 7-hydroxylation	Homo sapiens	106	ALA4421730	assay format	Patent Bioactivity Data
5.	ALA4422403	A	Inhibition of CYP3A4 in human liver microsomes assessed as reduction in enzyme-mediated testosterone 6-hydroxylation in presence of NADPH-generating system, G6P and G6P dehydrogenase	Homo sapiens	106	ALA4421730	microsome format	Patent Bioactivity Data
6.	ALA4422410	A	Inhibition of human CYP2E1 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method	Homo sapiens	43	ALA4421730	single protein format	Patent Bioactivity Data
7.	ALA4422411	A	Inhibition of human CYP2B6 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method	Homo sapiens	43	ALA4421730	single protein format	Patent Bioactivity Data
8.	ALA4422412	A	Inhibition of human CYP2C9 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method	Homo sapiens	43	ALA4421730	single protein format	Patent Bioactivity Data
9.	ALA4422413	A	Inhibition of human CYP2C19 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method	Homo sapiens	43	ALA4421730	single protein format	Patent Bioactivity Data
10.	ALA4422414	A	Inhibition of human CYP2D6 assessed as reduction in specific vivid-blue substrate O-dealkylation by modified PanVera vivid assay protocol based method	Homo sapiens	43	ALA4421730	single protein format	Patent Bioactivity Data
11.	ALA4422415	B	Selectivity index, ratio of IC50 for inhibition of human CYP2E1 to IC50 for inhibition of human CYP3A4	Homo sapiens	42	ALA4421730	assay format	Patent Bioactivity Data
12.	ALA4422416	B	Selectivity index, ratio of IC50 for inhibition of human CYP2B6 to IC50 for inhibition of human CYP3A4	Homo sapiens	42	ALA4421730	assay format	Patent Bioactivity Data
13.	ALA4422417	B	Selectivity index, ratio of IC50 for inhibition of human CYP2C9 to IC50 for inhibition of human CYP3A4	Homo sapiens	42	ALA4421730	assay format	Patent Bioactivity Data
14.	ALA4422418	B	Selectivity index, ratio of IC50 for inhibition of human CYP21C9 to IC50 for inhibition of human CYP3A4	Homo sapiens	42	ALA4421730	assay format	Patent Bioactivity Data
15.	ALA4422419	B	Selectivity index, ratio of IC50 for inhibition of human CYP2D6 to IC50 for inhibition of human CYP3A4	Homo sapiens	42	ALA4421730	assay format	Patent Bioactivity Data
16.	ALA4422428	A	Inhibition of CYP2A13 (unknown origin) at 1 uM relative to control	Homo sapiens	35	ALA4421730	single protein format	Patent Bioactivity Data
17.	ALA4422429	A	Inhibition of mouse CYP2A5 (unknown origin)	Mus musculus	35	ALA4421730	single protein format	Patent Bioactivity Data
18.	ALA4422431	B	Inhibition of human CYP2A6 expressed in insect cell membranes assessed as reduction in enzyme-mediated coumarin 7-hydroxylation in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and NADPH-generating system by fluorometry	Homo sapiens	55	ALA4421730	cell-based format	Patent Bioactivity Data