#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3705712	B	Inhibition Assay (Testosterone Hydroxylase): To gain insight into the selectivity of the synthetic compounds, nicotine, nicotine related alkaloids and nicotine metabolites for inhibition of other CYPs, we examined the major CYP present in human liver (i.e., CYP 3A4). That the CYP2A6 inhibitors showed low or no inhibitory activity against CYP3A4 suggests that the inhibitors examined selectively inhibited CYP2A6.	Homo sapiens	22		assay format	BindingDB Database
2.	ALA3705713	B	Inhibition Assay: The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay (Greenlee et al., J Pharmacol Exp Ther, 1978). Our first studies were with highly purified human CYP2A6 that provided a convenient and relatively high-throughput measure of CYP2A6 inhibition.	Homo sapiens	89		single protein format	BindingDB Database
3.	ALA4422401	B	Inhibition of human CYP2A6 expressed in insect cell microsomes assessed as reduction in enzyme-mediated coumarin 7-hydroxylation	Homo sapiens	111		assay format	Patent Bioactivity Data
4.	ALA4422402	B	Selectivity index, ratio of IC50 for inhibition of human CYP3A4 assessed as reduction in enzyme-mediated testosterone 6-hydroxylation to IC50 for inhibition of human CYP2A6 assessed as reduction in enzyme-mediated coumarin 7-hydroxylation	Homo sapiens	106		assay format	Patent Bioactivity Data
5.	ALA4422403	A	Inhibition of CYP3A4 in human liver microsomes assessed as reduction in enzyme-mediated testosterone 6-hydroxylation in presence of NADPH-generating system, G6P and G6P dehydrogenase	Homo sapiens	106		microsome format	Patent Bioactivity Data
6.	ALA4422404	B	Inhibition of CYP2A6 in human liver microsomes assessed as reduction in CYP2A6-mediated nicotine oxidase activity using [3H]-nicotine in presence of NADPH-generating system incubated for 20 mins by TLC/radiometric assay	Homo sapiens	7		microsome format	Patent Bioactivity Data
7.	ALA4422405	B	Binding affinity to Lymnaea stagnalis nicotinic acetylcholine receptor by fluorescence based assay	Lymnaea stagnalis	11		single protein format	Patent Bioactivity Data
8.	ALA4422430	B	Displacement of [125I]bungarotoxin from Lymnaea stagnalis nicotinic acetylcholine receptor assessed as residual radioligand binding relative to control	Lymnaea stagnalis	5		single protein format	Patent Bioactivity Data