# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3431930 | Binding | SUPPLEMENTARY: Inhibition of Carnitine palmitoyltransferase 1, muscle isoform | Homo sapiens | 476 | ALA3431459 | single protein format | Deposited Supplementary Bioactivity Data | |
2. | ALA3431931 | Binding | SUPPLEMENTARY: Inhibition of Carnitine palmitoyltransferase 2 | Homo sapiens | 476 | ALA3431459 | single protein format | Deposited Supplementary Bioactivity Data | |
3. | ALA3431933 | Binding | SUPPLEMENTARY: Inhibition of Carnitine palmitoyltransferase 1, liver isoform | Homo sapiens | 476 | ALA3431459 | assay format | Deposited Supplementary Bioactivity Data | |
4. | ALA3431934 | Binding | SUPPLEMENTARY: Inhibition of Carnitine palmitoyltransferase 2 | Rattus norvegicus | 455 | ALA3431459 | single protein format | Deposited Supplementary Bioactivity Data | |
5. | ALA3431935 | Physicochemical | SUPPLEMENTARY: Lyophilisation Solubility Assay (LYSA) | 405 | ALA3431459 | small-molecule physicochemical format | Deposited Supplementary Bioactivity Data | ||
6. | ALA3431936 | Physicochemical | SUPPLEMENTARY: Lipophilicity (log D) Determination by high-throughput shake-flask | 360 | ALA3431459 | small-molecule physicochemical format | Deposited Supplementary Bioactivity Data | ||
7. | ALA3431937 | Physicochemical | SUPPLEMENTARY: PAMPA permeability assay | 400 | ALA3431459 | small-molecule physicochemical format | Deposited Supplementary Bioactivity Data | ||
8. | ALA3540573 | Binding | Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake | Homo sapiens | 85 | ALA3526080 | cell membrane format | Scientific Literature | |
9. | ALA3540574 | Binding | Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake | Rattus norvegicus | 85 | ALA3526080 | cell membrane format | Scientific Literature | |
10. | ALA3540575 | ADME | Unbound Cmax in human plasma | Homo sapiens | 85 | ALA3526080 | cell-free format | Scientific Literature | |
11. | ALA3534882 | ADME | Time dependent inhibition of CYP1A2 (unknown origin) at 100 uM by LC/MS system | Homo sapiens | 42 | ALA3526118 | single protein format | Scientific Literature | |
12. | ALA3534883 | ADME | Time dependent inhibition of CYP2B6 (unknown origin) at 100 uM by LC/MS system | Homo sapiens | 34 | ALA3526118 | single protein format | Scientific Literature | |
13. | ALA3534884 | ADME | Time dependent inhibition of CYP2C9 (unknown origin) at 100 uM by LC/MS system | Homo sapiens | 35 | ALA3526118 | single protein format | Scientific Literature | |
14. | ALA3534885 | ADME | Time dependent inhibition of CYP2C19 in human liver microsomes at 100 uM by LC/MS system | Homo sapiens | 38 | ALA3526118 | assay format | Scientific Literature | |
15. | ALA3534886 | ADME | Time dependent inhibition of CYP2D6 (unknown origin) at 100 uM by LC/MS system | Homo sapiens | 37 | ALA3526118 | single protein format | Scientific Literature | |
16. | ALA3534887 | ADME | Time dependent inhibition of CYP3A4 (unknown origin) at 100 uM by LC/MS system | Homo sapiens | 35 | ALA3526118 | single protein format | Scientific Literature | |
17. | ALA3534888 | ADME | Covalent binding in human liver microsomes measured per mg of protein using radiolabelled compound at 10 uM after 1 hr incubation by liquid scintillation counting | Homo sapiens | 42 | ALA3526118 | assay format | Scientific Literature | |
18. | ALA3534889 | ADME | Metabolic activation in human liver microsomes assessed as [3H]GSH adduct formation rate measured per mg of protein at 100 uM by [3H]GSH trapping assay | Homo sapiens | 42 | ALA3526118 | assay format | Scientific Literature | |
19. | ALA3534892 | ADME | Time dependent inhibition of CYP2C8 (unknown origin) at 30 uM by LC/MS system | Homo sapiens | 2 | ALA3526118 | single protein format | Scientific Literature | |
20. | ALA3534905 | ADME | Intrinsic clearance for reactive metabolites formation per mg of protein in human liver microsomes based on [3H]GSH adduct formation rate at 100 uM by [3H]GSH trapping assay | Homo sapiens | 42 | ALA3526118 | assay format | Scientific Literature |