# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3705165 | B | Enzyme Assay: The inhibition of ALK tyrosine kinase activity may be demonstrated using known methods, for example using the recombinant kinase domain of the ALK in analogy to the VEGF-R kinase assay described in J. Wood et al. Cancer Res. 60, 2178-2189 (2000). | Homo sapiens | 61 | ALA3638924 | single protein format | BindingDB Database | |
2. | ALA4716830 | B | Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-Glo luciferase assay | Homo sapiens | 18 | ALA4715698 | cell-based format | Scientific Literature | |
3. | ALA4716832 | B | Inhibition of Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-Glo luciferase assay | Homo sapiens | 18 | ALA4715698 | cell-based format | Scientific Literature | |
4. | ALA4716833 | A | Antiproliferative activity against wild type mouse BaF3 cells assessed as reduction in cell growth incubated for 2 to 3 days by Bright-Glo luciferase assay | Mus musculus | 18 | ALA4715698 | cell-based format | Scientific Literature | |
5. | ALA4716887 | B | Selectivity ratio of IC50 for NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation to IC50 for Tel fused InsR (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation | 10 | ALA4715698 | cell-based format | Scientific Literature |