# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3757989 | Functional | Neuroprotective against IFNgamma/LPS stimulated THP1 condition medium-induced neurotoxicity in human SH-SY5Y cells assessed as increase in cytoplasmic IkappaBalpha level pretreated for 1 hr followed by addition of THP1 conditioned medium by western blot analysis | Homo sapiens | 1 | ALA3751843 | cell-based format | Scientific Literature | |
2. | ALA664050 | Binding | Compound was evaluated for interaction with the creatine kinase in rabbit muscle after 6 hr | Oryctolagus cuniculus | 4 | ALA1130374 | single protein format | Scientific Literature | |
3. | ALA680085 | Binding | Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras-CVLS by farnesyl transferase | Homo sapiens | 8 | ALA1136310 | protein complex format | Scientific Literature | |
4. | ALA682844 | Binding | Activity against Farnesyltransferase | 10 | ALA1130144 | protein complex format | Scientific Literature | ||
5. | ALA686125 | Binding | Inhibition of [3H]-GGPP incorporation into recombinant human Ha-Ras-CVLL by Geranylgeranyl transferase type I | Homo sapiens | 8 | ALA1136310 | protein complex format | Scientific Literature | |
6. | ALA699669 | Functional | Inhibition of K-Ras-transformed fibrosarcoma growth | 1 | ALA1130144 | assay format | Scientific Literature | ||
7. | ALA1109909 | Functional | Antitrypanosomal activity against Trypanosoma brucei brucei 427-221a after 40 hrs by bioluminescence assay | Trypanosoma brucei brucei | 24 | ALA1156161 | organism-based format | Scientific Literature | |
8. | ALA1109910 | Binding | Inhibition of Trypanosoma brucei brucei recombinant rhodesain after 5 mins by spectrofluorimetry | Trypanosoma brucei brucei | 23 | ALA1156161 | assay format | Scientific Literature | |
9. | ALA1109911 | Binding | Inhibition of Trypanosoma brucei brucei recombinant cathepsin B assessed after 5 mins by spectrofluorimetry | Trypanosoma brucei brucei | 23 | ALA1156161 | assay format | Scientific Literature | |
10. | ALA1109912 | ADME | Cytotoxicity against human Jurkat cells after 40 hrs bioluminescence assay | Homo sapiens | 19 | ALA1156161 | cell-based format | Scientific Literature | |
11. | ALA1109919 | Functional | Cytotoxicity against human HeLa cells | Homo sapiens | 3 | ALA1156161 | cell-based format | Scientific Literature | |
12. | ALA1109920 | ADME | Cytotoxicity against HUVEC | Homo sapiens | 2 | ALA1156161 | cell-based format | Scientific Literature | |
13. | ALA1109921 | Functional | Cytotoxicity against human A549 cells | Homo sapiens | 2 | ALA1156161 | cell-based format | Scientific Literature | |
14. | ALA1109922 | ADME | Cytotoxicity against rainbow trout RTS11 cells | Oncorhynchus mykiss | 1 | ALA1156161 | cell-based format | Scientific Literature | |
15. | ALA1109923 | ADME | Cytotoxicity against rainbow trout RTG2 cells | Oncorhynchus mykiss | 1 | ALA1156161 | cell-based format | Scientific Literature | |
16. | ALA1109924 | ADME | Cytotoxicity against chinook salmon CHSE-214 cells | Oncorhynchus tshawytscha | 1 | ALA1156161 | cell-based format | Scientific Literature | |
17. | ALA1109925 | Functional | Antiprotozoal activity against Tetrahymena pyriformis | Tetrahymena pyriformis | 1 | ALA1156161 | organism-based format | Scientific Literature | |
18. | ALA1110814 | Binding | Inhibition of PAF | 3 | ALA1156161 | assay format | Scientific Literature | ||
19. | ALA1110815 | Binding | Inhibition of Mycobacterium tuberculosis mycothiol-S-conjugate amidase | Mycobacterium tuberculosis | 2 | ALA1156161 | single protein format | Scientific Literature | |
20. | ALA1110816 | Binding | Activation of NF-kappaB in human jurkat cells assessed as active concentration required | Homo sapiens | 1 | ALA1156161 | cell-based format | Scientific Literature |