#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3705116	B	Biological Assay Example 9: The inhibition of recombinant CYP2C9 by compounds of the invention was measured using a commercial kit from Invitrogen (cat #2859).	Homo sapiens	21	ALA3638974	single protein format	BindingDB Database
2.	ALA3705117	B	Biological Assay Example 8: Using a procedure similar to that described in Biological Test Example 6, the inhibition of cytochrome P450 2C19-isoenzyme catalysed N-demethylation of [N-methyl-14C]-Diazepam by the test compound was assayed at 37° C. with human recombinant cytochrome P450 2C19.	Homo sapiens	42	ALA3638974	single protein format	BindingDB Database
3.	ALA3705118	B	Biological Assay Example 7: Using a procedure similar to that described in Biological Test Example 6, the inhibition of cytochrome P450 2C9-isoenzyme catalysed O-demethylation of [O-methyl-14C]-Naproxen by the test compound was assayed at 37° C. with human recombinant cytochrome P450 2C9.	Homo sapiens	42	ALA3638974	single protein format	BindingDB Database
4.	ALA3705119	B	Biological Assay Example 4: Inhibition assay using 11β-HSD1 in the presence of 50% human plasma.	Homo sapiens	85	ALA3638974	single protein format	BindingDB Database
5.	ALA3705120	B	Biological Assay Example 6: The assay was based on a method published by Moody et al. (Xenobiotica 1999). The inhibition of cytochrome P450 3A4-isoenzyme catalysed N-demethylation of [N-methyl-14C]-Erythromycin by the test compound was assayed at 37° C with human recombinant cytochrome P450 3A4.	Homo sapiens	42	ALA3638974	single protein format	BindingDB Database
6.	ALA3705121	B	Biological Assay Example 1: The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, S. S. Mundt, H. J. Zokian, G. J. Ding, A. Hermanowski-Vosatka, B. Strulovici, and W. Zheng, High-Throughput Screening of 11-Beta-Hydroxyseroid Dehydrogenase Type 1 in Scintillation Proximity Assay Format. Assay Drug Dev Technol 3 (2005) 377-384).	Homo sapiens	98	ALA3638974	assay format	BindingDB Database
7.	ALA4036184	A	Inhibition of CYP2D6 (unknown origin)	Homo sapiens	12	ALA4033714	single protein format	Scientific Literature
8.	ALA4036188	A	Dose normalized AUC in iv dosed cynomolgus monkey	Macaca fascicularis	4	ALA4033714	organism-based format	Scientific Literature
9.	ALA4036189	B	Inhibition of human 11beta-HSD1 expressed in CHO cell microsomes using [3H]cortisone as substrate preincubated with substrate for 10 mins followed by enzyme addition measured after 90 mins by microbeta scintillation proximity assay	Homo sapiens	43	ALA4033714	assay format	Scientific Literature
10.	ALA4036190	B	Inhibition of 11beta-HSD1 in human omental adipocytes using [3H]cortisone as substrate preincubated for 1 hr followed by substrate addition measured after 3 to 4 hrs by scintillation proximity assay	Homo sapiens	40	ALA4033714	cell-based format	Scientific Literature
11.	ALA4036191	A	Half life in rat liver microsomes	Rattus norvegicus	24	ALA4033714	assay format	Scientific Literature
12.	ALA4036192	A	Inhibition of recombinant CYP3A4 (unknown origin)	Homo sapiens	26	ALA4033714	single protein format	Scientific Literature
13.	ALA4036193	P	Aqueous solubility of the compound		6	ALA4033714	small-molecule physicochemical format	Scientific Literature
14.	ALA4036194	A	Half life in human liver microsomes	Homo sapiens	15	ALA4033714	assay format	Scientific Literature
15.	ALA4036195	B	Inhibition of human ERG	Homo sapiens	3	ALA4033714	single protein format	Scientific Literature
16.	ALA4036196	A	Inhibition of CYP2C9 (unknown origin)	Homo sapiens	12	ALA4033714	single protein format	Scientific Literature
17.	ALA4036197	A	Half life in cynomolgus monkey liver microsomes	Macaca fascicularis	11	ALA4033714	assay format	Scientific Literature
18.	ALA4036198	B	Inhibition of human ERG at 10 uM by patch clamp assay relative to control	Homo sapiens	5	ALA4033714	assay format	Scientific Literature
19.	ALA4036199	B	Inhibition of 11beta-HSD1 in primary human adipocytes assessed as reduction in conversion of cortisone to cortisol using cortisone as substrate incubated overnight by HTRF assay	Homo sapiens	6	ALA4033714	cell-based format	Scientific Literature
20.	ALA4036200	A	Mean residence time in iv dosed cynomolgus monkey	Macaca fascicularis	4	ALA4033714	organism-based format	Scientific Literature