# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA621252 | A | Clearance in rat after oral administration at 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
2. | ALA620195 | A | Volume distribution in rat after oral administration at 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
3. | ALA622911 | A | AUC in rat brain after oral administration at 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
4. | ALA622914 | A | AUC in rat plasma after oral administration at 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
5. | ALA622835 | A | Half-life in rat after oral administration at 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA622901 | A | Oral bioavailability in rat after oral administration at 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
7. | ALA624653 | A | Compound was tested for brain/plasma ratio after oral administration at 10 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA625041 | P | Calculated partition coefficient (clogP) | 29 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA636810 | P | Partition coefficient (logP) | 1 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA666465 | B | Binding affinity to the cloned human corticotropin releasing factor receptor 1 | 28 | single protein format | Scientific Literature | |||
11. | ALA872976 | F | Inhibition of CRF-stimulated ACTH release in cultured rat anterior pituitary cells | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
12. | ALA796425 | F | Inhibition of CRF-stimulated cAMP production in cultured rat anterior pituitary cells | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
13. | ALA839639 | B | Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptor | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
14. | ALA828240 | B | Inhibition of [125I]o-CRF binding to CHO cells expressing human CRF1 receptor | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
15. | ALA5121331 | P | Thermodynamic aqueous solubility of the compound | 163 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA5121332 | P | Lipophilicity, logD of compound | 18 | small-molecule physicochemical format | Scientific Literature | |||
17. | ALA5121348 | F | Antagonist activity at human CRF1 receptor | Homo sapiens | 2 | assay format | Scientific Literature |