# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA884263 | F | Inhibitory concentration on de novo synthesis of sphingomyelin (SM) by metabolic labeling of lipids in CHO cells with radioactive serine | Cricetulus griseus | 8 | ALA1145053 | cell-based format | Scientific Literature | |
2. | ALA652134 | F | Effect of compound on de novo synthesis of sphingomyelin (SM) by metabolic labeling of lipids in CHO cells with radioactive serine at 1 uM | Cricetulus griseus | 8 | ALA1145053 | cell-based format | Scientific Literature | |
3. | ALA1250124 | F | Antiviral activity against Hepatitis C virus (isolate Con1) genotype 1b in human Huh-7/3-1 cells assessed as inhibition of HCV replication after 72 hrs by luciferase assay | Hepacivirus hominis | 5 | ALA1240304 | organism-based format | Scientific Literature | |
4. | ALA1250184 | A | Cytotoxicity against human Huh-7/3-1 cells assessed as cell viability at 0.1 to 11 uM after 72 hrs by WST-8 assay | Homo sapiens | 1 | ALA1240304 | cell-based format | Scientific Literature | |
5. | ALA3405666 | B | Binding affinity to His-tagged human recombinant START domain-containing protein 7 containing CERT START domain expressed in Escherichia coli assessed as bound fluorescent ceramide probe level TALON metal affinity resin at 200 pmol incubated for 30 mins assessed as by fluorescent binding assay | Homo sapiens | 4 | ALA3400071 | assay format | Scientific Literature | |
6. | ALA3405855 | B | Binding affinity to histidine-tagged human recombinant COL4A3ABP containing CERT START domain pre-incubated for 30 mins before biotinylated ceramide probe addition and measured after 18 hrs post probe addition by TR-FRET binding assay | Homo sapiens | 4 | ALA3400071 | single protein format | Scientific Literature |