| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA669982 | Binding | Inhibitory concentration against Dihydrofolate reductase from Mycobacterium avium (Mycobacterium avium) | Mycobacterium avium | 10 | ALA1148359 | single protein format | Scientific Literature | |
| 2. | ALA669983 | Binding | Inhibition of Dihydrofolate reductase from Pneumocystis carinii (Pneumocystis carinii) | Pneumocystis carinii | 11 | ALA1148359 | single protein format | Scientific Literature | |
| 3. | ALA668092 | Binding | Inhibitory concentration against Dihydrofolate reductase from Toxoplasma gondii (Toxoplasma gondii) | Toxoplasma gondii | 11 | ALA1148359 | single protein format | Scientific Literature | |
| 4. | ALA668095 | Binding | Inhibitory concentration against Dihydrofolate reductase from rat liver | Rattus norvegicus | 11 | ALA1148359 | assay format | Scientific Literature | |
| 5. | ALA841117 | Binding | Selectivity ratio (IC50 rlDHFR)/(IC50 maDHFR) | 10 | ALA1148359 | assay format | Scientific Literature | ||
| 6. | ALA841118 | Binding | Selectivity ratio (IC50rlDHFR)/(IC50 tgDHFR) | 11 | ALA1148359 | assay format | Scientific Literature | ||
| 7. | ALA841119 | Binding | Selectivity ratio [(IC50 rlDHFR)/(IC50 pcDHFR) | 10 | ALA1148359 | assay format | Scientific Literature | ||
| 8. | ALA889606 | Binding | Inhibition of Pneumocystis carinii DHFR | Pneumocystis carinii | 22 | ALA1145401 | single protein format | Scientific Literature | |
| 9. | ALA889609 | Binding | Inhibition of Toxoplasma gondii DHFR | Toxoplasma gondii | 23 | ALA1145401 | single protein format | Scientific Literature | |
| 10. | ALA889610 | Binding | Inhibition of Mycobacterium avium DHFR | Mycobacterium avium | 23 | ALA1145401 | single protein format | Scientific Literature | |
| 11. | ALA907539 | Binding | Inhibition of rat liver DHFR | Rattus norvegicus | 23 | ALA1145401 | assay format | Scientific Literature | |
| 12. | ALA907540 | Binding | Selectivity ratio of IC50 for rat liver DHFR to IC50 for Pneumocystis carinii DHFR | 23 | ALA1145401 | assay format | Scientific Literature | ||
| 13. | ALA907541 | Binding | Selectivity ratio of IC50 for rat liver DHFR to IC50 for Toxoplasma gondii DHFR | 23 | ALA1145401 | assay format | Scientific Literature | ||
| 14. | ALA907542 | Binding | Selectivity ratio of IC50 for rat liver DHFR to IC50 for Mycobacterium avium DHFR | 23 | ALA1145401 | assay format | Scientific Literature | ||
| 15. | ALA1071424 | Binding | Inhibition of Toxoplasma gondii DHFR by spectrophotometric assay | Toxoplasma gondii | 80 | ALA1156926 | single protein format | Scientific Literature | |
| 16. | ALA1071425 | Binding | Inhibition of rat liver DHFR by spectrophotometric assay | Rattus norvegicus | 80 | ALA1156926 | assay format | Scientific Literature | |
| 17. | ALA4224045 | Binding | Inhibition of Pneumocystis jirovecii recombinant DHFR expressed in Escherichia coli Rosetta Gami B (DE3) competent cells using DHFA as substrate and NADPH | Pneumocystis jirovecii | 20 | ALA4219246 | cell-based format | Scientific Literature | |
| 18. | ALA4224046 | ADME | Inhibition of human recombinant DHFR expressed in Escherichia coli Rosetta Gami B (DE3) competent cells using DHFA as substrate and NADPH | Homo sapiens | 20 | ALA4219246 | cell-based format | Scientific Literature | |
| 19. | ALA4224047 | Toxicity | Selectivity ratio of IC50 for human recombinant DHFR to IC50 for Pneumocystis jirovecii recombinant DHFR | 20 | ALA4219246 | assay format | Scientific Literature |
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