# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3720764 | F | Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay | Homo sapiens | 167 | ALA3714716 | cell-based format | Patent Bioactivity Data | |
2. | ALA3720765 | F | Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay relative to forskolin | Homo sapiens | 167 | ALA3714716 | cell-based format | Patent Bioactivity Data | |
3. | ALA3720769 | F | Agonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay | Homo sapiens | 8 | ALA3714716 | cell-based format | Patent Bioactivity Data | |
4. | ALA3720770 | F | Agonist activity at RXFP2 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay relative to control | Homo sapiens | 8 | ALA3714716 | cell-based format | Patent Bioactivity Data | |
5. | ALA3720771 | F | Agonist activity at vasopressin receptor 1b (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay | Homo sapiens | 8 | ALA3714716 | cell-based format | Patent Bioactivity Data | |
6. | ALA3720772 | F | Agonist activity at vasopressin receptor 1b (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay relative to control | Homo sapiens | 8 | ALA3714716 | cell-based format | Patent Bioactivity Data | |
7. | ALA3720773 | A | Cytotoxic activity against HEK293 cells assessed as reduction in cell viability by measuring ATP level incubated for 72 hrs by ATP cytotoxicity assay | Homo sapiens | 8 | ALA3714716 | cell-based format | Patent Bioactivity Data | |
8. | ALA3720774 | A | Cytotoxic activity against HEK293 cells assessed as reduction in cell viability by measuring ATP level incubated for 72 hrs by ATP cytotoxicity assay relative to control | Homo sapiens | 8 | ALA3714716 | cell-based format | Patent Bioactivity Data | |
9. | ALA3720775 | P | Solubility in PBS buffer | 8 | ALA3714716 | small-molecule physicochemical format | Patent Bioactivity Data | ||
10. | ALA3720776 | A | Half life in mouse liver microsomes | Mus musculus | 5 | ALA3714716 | tissue-based format | Patent Bioactivity Data | |
11. | ALA4156525 | F | Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay | Homo sapiens | 57 | ALA4152336 | cell-based format | Scientific Literature | |
12. | ALA4156526 | F | Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay relative to forskloin | Homo sapiens | 56 | ALA4152336 | cell-based format | Scientific Literature |