# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3720849 | B | Inhibition of human KIAA1361 kinase domain (2 to 322 residues) expressed in baculovirus assessed as remaining ATP level incubated for 2 hrs by luciferase-luciferin coupled chemiluminescent kinase assay | Homo sapiens | 98 | ALA3714752 | assay format | Patent Bioactivity Data | |
2. | ALA3720850 | B | Inhibition of human JIK kinase domain (2 to 318 residues) expressed in baculovirus assessed as remaining ATP level incubated for 2 hrs by luciferase-luciferin coupled chemiluminescent kinase assay | Homo sapiens | 98 | ALA3714752 | assay format | Patent Bioactivity Data | |
3. | ALA3720851 | B | Inhibition of human TAO kinase domain (2 to 322 residues) expressed in baculovirus assessed as remaining ATP level incubated for 2 hrs by luciferase-luciferin coupled chemiluminescent kinase assay | Homo sapiens | 98 | ALA3714752 | assay format | Patent Bioactivity Data | |
4. | ALA4479294 | B | Inhibition of TAOK2 in human U2OS cells assessed as inhibition of cellular autophagy measured as P62 accumulation at 50 uM after 24 hrs by western blot analysis | Homo sapiens | 5 | ALA4477233 | cell-based format | Scientific Literature | |
5. | ALA4479295 | B | Inhibition of TAOK2 in human U2OS cells assessed as inhibition of cellular autophagy measured as GFP-LC3 accumulation at 50 uM after 24 hrs by flow cytometric analysis | Homo sapiens | 13 | ALA4477233 | cell-based format | Scientific Literature | |
6. | ALA4479296 | B | Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system using MBP as substrate measured after 30 mins in presence of [32P]ATP by radiometric assay | Rattus norvegicus | 2 | ALA4477233 | assay format | Scientific Literature | |
7. | ALA4479297 | B | Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substrate and [32P]ATP measured after 10 mins by Kinase-Glo assay | Rattus norvegicus | 56 | ALA4477233 | assay format | Scientific Literature | |
8. | ALA4479298 | B | Binding affinity to p38 (unknown origin) assessed as change in melting temperature at 1 uM by SYPRO orange dye-based DSF analysis | Homo sapiens | 9 | ALA4477233 | protein format | Scientific Literature | |
9. | ALA4479299 | B | Binding affinity to ASK1 (unknown origin) assessed as change in melting temperature at 1 uM by SYPRO orange dye-based DSF analysis | Homo sapiens | 9 | ALA4477233 | single protein format | Scientific Literature | |
10. | ALA4479300 | B | Binding affinity to rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as change in melting temperature at 1 uM by SYPRO orange dye-based DSF analysis | Rattus norvegicus | 13 | ALA4477233 | assay format | Scientific Literature | |
11. | ALA4479307 | B | Inhibition of human TAO2 | Homo sapiens | 3 | ALA4477233 | single protein format | Scientific Literature |