# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3721246 | B | Inhibition of human PFKFB3 expressed in Escherichia coli BL21 (DE3) assessed as reduction in NADH consumption using fructose-6-phosphate incubated for 15 mins by spectrophotometry based pyruvate kinase and LDH enzyme coupled kinetic assay | Homo sapiens | 6 | assay format | Patent Bioactivity Data | ||
2. | ALA3720724 | F | Inhibition of cell proliferation of human Jurkat cells incubated for 72 hrs by Alamar blue assay | Homo sapiens | 25 | cell-based format | Patent Bioactivity Data | ||
3. | ALA3720726 | F | Inhibition of cell proliferation of human NCI-H82 cells incubated for 72 hrs by Alamar blue assay | Homo sapiens | 11 | cell-based format | Patent Bioactivity Data | ||
4. | ALA3720728 | F | Inhibition of cell proliferation of human NCI-H1437 cells incubated for 72 hrs by Alamar blue assay | Homo sapiens | 5 | cell-based format | Patent Bioactivity Data | ||
5. | ALA3720739 | A | Stability in pooled mixed gender human liver microsomes assessed drug metabolism at 37 degC after 30 mins by LC/MS-MS method | Homo sapiens | 6 | tissue-based format | Patent Bioactivity Data | ||
6. | ALA3720740 | P | Solubility in Cremophore:EToH:saline solution after 24 hrs at room temperature by HPLC method | 6 | small-molecule physicochemical format | Patent Bioactivity Data | |||
7. | ALA3720747 | F | Antitumor activity against human U87MG cells implanted in C57Bc16 mouse assessed as inhibition of tumor size at 20 mg/kg, ip measured during 7 to 25 days after tumor inoculation | Homo sapiens | 1 | organism-based format | Patent Bioactivity Data | ||
8. | ALA3720748 | F | Antitumor activity against mouse CT26 cells implanted in C57Bc16 mouse assessed as inhibition of tumor size at 20 or 23 mg/kg, ip measured during 7 to 22 days after tumor inoculation | Mus musculus | 1 | organism-based format | Patent Bioactivity Data |