# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3734283 | B | Inhibition of human GRK2 after 90 to 120 mins by Kinase-Glo assay | Homo sapiens | 97 | single protein format | Patent Bioactivity Data | ||
2. | ALA3734284 | B | Inhibition of GRK3 (unknown origin) after 90 to 120 mins by Kinase-Glo assay | Homo sapiens | 24 | single protein format | Patent Bioactivity Data | ||
3. | ALA3734285 | B | Inhibition of GRK5 (unknown origin) after 90 to 120 mins by Kinase-Glo assay | Homo sapiens | 24 | single protein format | Patent Bioactivity Data | ||
4. | ALA3734286 | B | Inhibition of GRK6 (unknown origin) after 90 to 120 mins by Kinase-Glo assay | Homo sapiens | 10 | single protein format | Patent Bioactivity Data | ||
5. | ALA3734288 | F | Antiglaucoma activity in cat assessed as decrease of hyperemia administered topically | Felis catus | 1 | organism-based format | Patent Bioactivity Data | ||
6. | ALA3734289 | B | Inhibition of GRK2 in human U2OS cells assessed as inhibition of isoproterenol-induced translocation of arrestin-GFP to beta 2 adrenergic receptor preincubated for 60 mins by Transfluor assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
7. | ALA3734290 | B | Inhibition of GRK2 in human U2OS cells assessed as inhibition of isoproterenol-induced translocation of arrestin-GFP to beta 1 adrenergic receptor preincubated for 60 mins by Transfluor assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
8. | ALA3734291 | B | Inhibition of GRK2 in human U2OS cells assessed as inhibition of morphine-induced translocation of arrestin-GFP to mu opioid receptor preincubated for 60 mins by Transfluor assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
9. | ALA3734292 | B | Inhibition of GRK2 in HEK293 cells overexpressing beta 2 adrenergic receptor assessed as increase in c-AMP accumulation in presence of isoproterenol | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
10. | ALA3734297 | F | Antiglaucoma activity in cat assessed as decrease of redness administered topically | Felis catus | 1 | organism-based format | Patent Bioactivity Data | ||
11. | ALA3734298 | F | Antiglaucoma activity in cat assessed as decrease of ocular irritation administered topically | Felis catus | 1 | organism-based format | Patent Bioactivity Data |