# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3734545 | Binding | Inhibition of recombinant human STIM1/Orai1 expressed in HEK293 cells assessed as inhibition of peak basal signal after 30 mins by fluo4-AM dye-based FLIPR assay | Homo sapiens | 78 | ALA3727365 | cell-based format | Patent Bioactivity Data | |
2. | ALA3734546 | Binding | Inhibition of STIM1/Orai1 in rat RBL2H3 cells assessed as inhibition of upslope incubated for 5 mins followed by thapsigargin addition for 25 mins measured for 7 secs by fluo4-AM dye-based FLIPR assay | Rattus norvegicus | 84 | ALA3727365 | cell-based format | Patent Bioactivity Data | |
3. | ALA3734547 | Functional | Inhibition of PHA/TPA-induced IL2 release in human Jurkat T cells preincubated for 10 mins followed by PHA/TPA stimulation measured after 20 mins by ELISA | Homo sapiens | 84 | ALA3727365 | cell-based format | Patent Bioactivity Data |
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