# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3734235 | B | Inhibition of human Nox2 expressed in COS7 cells co-transfected with human p22-phox,p47phox and p67-phox assessed as inhibition of PMA-induced superoxide generation by L-012 chemiluminescence analysis | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
2. | ALA3734236 | B | Inhibition of human Nox2 expressed in COS7 cells co-transfected with human p22-phox,p47phox and p67-phox assessed as inhibition of PMA-induced H2O2 production by amplex red dye based fluorescence assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
3. | ALA3734237 | B | Inhibition of human Nox4 expressed in COS7 cells assessed as inhibition of PMA-induced H2O2 production by amplex red dye based fluorescence assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
4. | ALA3734238 | B | Inhibition of bovine xanthine-oxidase assessed as H2O2 production at 25 to 50 uM by amplex red dye based fluorescence assay | Bos taurus | 17 | single protein format | Patent Bioactivity Data | ||
5. | ALA3734240 | B | Inhibition of human Nox1 expressed in COS7 cells co-transfected with human NOXO1/NOXA1 assessed as inhibition of PMA-induced superoxide generation by L-012 chemiluminescence analysis | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
6. | ALA3734241 | B | Inhibition of Nox5 expressed in HEK cells assessed as inhibition of PMA/ionomycin-induced superoxide generation by L-012 chemiluminescence analysis | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
7. | ALA3734242 | B | Inhibition of Nox2 (unknown origin) | Homo sapiens | 2 | single protein format | Patent Bioactivity Data | ||
8. | ALA3734244 | F | Inhibition of high-glucose-stimulated superoxide production in HPAEC cells at 25 uM measured after 24 hrs | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
9. | ALA3734245 | F | Inhibition of angiotensin-2-stimulated superoxide production in HPAEC cells at 25 uM measured after 24 hrs | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
10. | ALA3734246 | B | Inhibition of Nox2 (unknown origin) assessed as inhibition of PMA-induced Nox2 and p47-phox interaction by immunoprecipitation analysis | Homo sapiens | 2 | single protein format | Patent Bioactivity Data | ||
11. | ALA3734248 | B | Inhibition of human Nox1 expressed in COS7 cells co-transfected with human co-transfected with human NOXO1/NOXA1 assessed as inhibition of PMA-induced ROS production at 10 uM | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
12. | ALA3734249 | F | Inhibition of high-glucose-stimulated ROS production in rat cardiomyocyte at 25 uM | Rattus norvegicus | 2 | assay format | Patent Bioactivity Data | ||
13. | ALA3734250 | F | Inhibition of high-glucose-stimulated hypertrophy in rat cardiomyocyte at 25 uM | Rattus norvegicus | 2 | assay format | Patent Bioactivity Data | ||
14. | ALA3734251 | F | Inhibition of PMA-induced ROS production in human fibroblast at 10 uM | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data |