# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3734235 | Binding | Inhibition of human Nox2 expressed in COS7 cells co-transfected with human p22-phox,p47phox and p67-phox assessed as inhibition of PMA-induced superoxide generation by L-012 chemiluminescence analysis | Homo sapiens | 18 | ALA3727360 | cell-based format | Patent Bioactivity Data | |
2. | ALA3734236 | Binding | Inhibition of human Nox2 expressed in COS7 cells co-transfected with human p22-phox,p47phox and p67-phox assessed as inhibition of PMA-induced H2O2 production by amplex red dye based fluorescence assay | Homo sapiens | 18 | ALA3727360 | cell-based format | Patent Bioactivity Data | |
3. | ALA3734237 | Binding | Inhibition of human Nox4 expressed in COS7 cells assessed as inhibition of PMA-induced H2O2 production by amplex red dye based fluorescence assay | Homo sapiens | 18 | ALA3727360 | cell-based format | Patent Bioactivity Data | |
4. | ALA3734238 | Binding | Inhibition of bovine xanthine-oxidase assessed as H2O2 production at 25 to 50 uM by amplex red dye based fluorescence assay | Bos taurus | 17 | ALA3727360 | single protein format | Patent Bioactivity Data | |
5. | ALA3734240 | Binding | Inhibition of human Nox1 expressed in COS7 cells co-transfected with human NOXO1/NOXA1 assessed as inhibition of PMA-induced superoxide generation by L-012 chemiluminescence analysis | Homo sapiens | 18 | ALA3727360 | cell-based format | Patent Bioactivity Data | |
6. | ALA3734241 | Binding | Inhibition of Nox5 expressed in HEK cells assessed as inhibition of PMA/ionomycin-induced superoxide generation by L-012 chemiluminescence analysis | Homo sapiens | 18 | ALA3727360 | cell-based format | Patent Bioactivity Data | |
7. | ALA3734242 | Binding | Inhibition of Nox2 (unknown origin) | Homo sapiens | 2 | ALA3727360 | single protein format | Patent Bioactivity Data | |
8. | ALA3734244 | Functional | Inhibition of high-glucose-stimulated superoxide production in HPAEC cells at 25 uM measured after 24 hrs | Homo sapiens | 2 | ALA3727360 | cell-based format | Patent Bioactivity Data | |
9. | ALA3734245 | Functional | Inhibition of angiotensin-2-stimulated superoxide production in HPAEC cells at 25 uM measured after 24 hrs | Homo sapiens | 2 | ALA3727360 | cell-based format | Patent Bioactivity Data | |
10. | ALA3734246 | Binding | Inhibition of Nox2 (unknown origin) assessed as inhibition of PMA-induced Nox2 and p47-phox interaction by immunoprecipitation analysis | Homo sapiens | 2 | ALA3727360 | single protein format | Patent Bioactivity Data | |
11. | ALA3734248 | Binding | Inhibition of human Nox1 expressed in COS7 cells co-transfected with human co-transfected with human NOXO1/NOXA1 assessed as inhibition of PMA-induced ROS production at 10 uM | Homo sapiens | 2 | ALA3727360 | cell-based format | Patent Bioactivity Data | |
12. | ALA3734249 | Functional | Inhibition of high-glucose-stimulated ROS production in rat cardiomyocyte at 25 uM | Rattus norvegicus | 2 | ALA3727360 | assay format | Patent Bioactivity Data | |
13. | ALA3734250 | Functional | Inhibition of high-glucose-stimulated hypertrophy in rat cardiomyocyte at 25 uM | Rattus norvegicus | 2 | ALA3727360 | assay format | Patent Bioactivity Data | |
14. | ALA3734251 | Functional | Inhibition of PMA-induced ROS production in human fibroblast at 10 uM | Homo sapiens | 2 | ALA3727360 | cell-based format | Patent Bioactivity Data |