# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3734216 | F | Increase in insulin release in mouse BetaTC6 cells assessed as relative insulin release activity at 10 uM incubated for 2 to 4 hrs by FRET based HTRF assay relative to sunitinib | Mus musculus | 355 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
2. | ALA3734218 | A | Cytotoxic activity against mouse C2C12 cells assessed as inhibition of cell proliferation of at 2 to 10 uM incubated for 72 hrs by MTT assay | Mus musculus | 9 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
3. | ALA3734219 | A | Cytotoxic activity against mouse BetaTC6 cells assessed as inhibition of cell proliferation at 2 to 10 uM incubated for 72 hrs by MTT assay | Mus musculus | 2 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
4. | ALA3734220 | B | Inhibition of Scyl1 in mouse BetaTC6 cells assessed as increase in insulin release at 5 uM incubated for 2 hrs by ELISA | Mus musculus | 7 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
5. | ALA3734221 | B | Inhibition of Scyl1 in mouse BetaTC6 cells assessed as increase in insulin release at 2 to 10 uM incubated for 2 hrs in presence of high glucose media by ELISA | Mus musculus | 5 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
6. | ALA3734222 | A | Effect on insulin release in mouse BetaTC6 cells assessed as ratio of insulin release incubated for 2 hrs in presence of low glucose media by ELISA relative to DMSO | Mus musculus | 7 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
7. | ALA3734256 | B | Inhibition of Scyl1 in mouse C2C12 cells assessed as insulin-dependent increase of 2-NBDG uptake (Rvb = 11.78 +/- 1.22%) | Mus musculus | 1 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
8. | ALA3734259 | A | Cytotoxic activity against mouse C2C12 cells assessed as inhibition of cell proliferation of at 2 uM incubated for 72 hrs by MTT assay | Mus musculus | 3 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
9. | ALA3734260 | B | Inhibition of Scyl1 in mouse BetaTC6 cells assessed as reduction in increase in insulin release at 5 uM incubated for 2 hrs by ELISA | Mus musculus | 1 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
10. | ALA3734261 | B | Inhibition of Scyl1 in mouse BetaTC6 cells assessed as reduction in increase in insulin release incubated for 2 hrs by ELISA | Mus musculus | 1 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
11. | ALA3734262 | B | Inhibition of Scyl1 in mouse BetaTC6 cells assessed as ratio of insulin release at 2 uM incubated for 2 hrs by ELISA relative to DMSO (Rvb = 1 No_unit) | Mus musculus | 5 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
12. | ALA3734263 | B | Inhibition of Scyl1 in mouse BetaTC6 cells assessed as ratio of insulin release at 5 uM incubated for 2 hrs by ELISA relative to DMSO (Rvb = 1 No_unit) | Mus musculus | 5 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
13. | ALA3734264 | B | Inhibition of Scyl1 in mouse BetaTC6 cells assessed as ratio of insulin release at 10 uM incubated for 2 hrs by ELISA relative to DMSO (Rvb = 1 No_unit) | Mus musculus | 5 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
14. | ALA3734265 | B | Inhibition of Scyl1 in mouse C2C12 cells assessed as increase in 2-NBDG uptake at 5 uM after 1 hr relative to DMSO | Mus musculus | 7 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
15. | ALA3734266 | B | Inhibition of Scyl1 in mouse BetaTC6 cells assessed as increase in 2-NBDG uptake at 5 uM after 1 hr relative to DMSO | Mus musculus | 7 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
16. | ALA3734277 | B | Inhibition of Scyl1 in mouse C2C12 cells assessed as insulin release by ELISA | Mus musculus | 1 | ALA3727361 | cell-based format | Patent Bioactivity Data |