# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3734216 | F | Increase in insulin release in mouse BetaTC6 cells assessed as relative insulin release activity at 10 uM incubated for 2 to 4 hrs by FRET based HTRF assay relative to sunitinib | Mus musculus | 355 | ALA3727361 | cell-based format | Patent Bioactivity Data | |
2. | ALA4483863 | F | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Plasmodium berghei | 9,989 | ALA4483862 | organism-based format | Winzeler Lab Plasmodium Screening Data | |
3. | ALA4483864 | F | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Homo sapiens | 9,989 | ALA4483862 | cell-based format | Winzeler Lab Plasmodium Screening Data |