# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3737695 | Binding | Inhibition of human recombinant SphK1 at 500 uM preincubated for 5 mins followed by substrate addition measured for 60 mins by plate reader assay | Homo sapiens | 6 | ALA3734711 | single protein format | Scientific Literature | |
2. | ALA3737696 | Binding | Inhibition of human recombinant SphK1 at 50 uM preincubated for 5 mins followed by substrate addition measured for 60 mins by plate reader assay | Homo sapiens | 3 | ALA3734711 | single protein format | Scientific Literature | |
3. | ALA3737697 | Binding | Inhibition of human recombinant SphK2 at 500 uM preincubated for 5 mins followed by substrate addition measured for 60 mins by plate reader assay | Homo sapiens | 3 | ALA3734711 | single protein format | Scientific Literature | |
4. | ALA3737698 | Binding | Inhibition of human recombinant SphK2 at 50 uM preincubated for 5 mins followed by substrate addition measured for 60 mins by plate reader assay | Homo sapiens | 3 | ALA3734711 | single protein format | Scientific Literature | |
5. | ALA3737699 | Binding | Inhibition of human recombinant SphK1 preincubated for 5 mins followed by substrate addition measured for 60 mins by plate reader assay | Homo sapiens | 4 | ALA3734711 | single protein format | Scientific Literature | |
6. | ALA3737700 | Binding | Inhibition of human recombinant SphK2 preincubated for 5 mins followed by substrate addition measured for 60 mins by plate reader assay | Homo sapiens | 4 | ALA3734711 | single protein format | Scientific Literature | |
7. | ALA3737701 | Functional | Antiproliferative activity against human U937 cells after 72 hrs by MTT assay | Homo sapiens | 1 | ALA3734711 | cell-based format | Scientific Literature | |
8. | ALA3816960 | Binding | Inhibition of GST-tagged full length human recombinant SPHK1 expressed in baculovirus using sphingosine as substrate preincubated for 10 mins measured after 1 hr by ADP-quest assay | Homo sapiens | 52 | ALA3813598 | assay format | Scientific Literature | |
9. | ALA3816961 | Binding | Inhibition of GST-tagged full length human recombinant SPHK2 expressed in baculovirus using sphingosine as substrate preincubated for 10 mins measured after 1 hr by ADP-quest assay | Homo sapiens | 52 | ALA3813598 | assay format | Scientific Literature |