#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3737385	Functional	Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux in presence of EC20 glutamate	Homo sapiens	21	ALA3734684	cell-based format	Scientific Literature
2.	ALA3737386	Functional	Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as Ca2+ flux upto 25 uM relative to glutamate	Homo sapiens	20	ALA3734684	cell-based format	Scientific Literature
3.	ALA3738332	Binding	Positive allosteric modification of mGlu5 receptor in rat cortical astrocytes assessed as maximal leftward shift in the EC50 of glutamate induced response upto 25 uM	Rattus norvegicus	20	ALA3734684	cell-based format	Scientific Literature
4.	ALA3738333	ADME	Intrinsic clearance in human liver microsomes at 3 uM	Homo sapiens	3	ALA3734684	tissue-based format	Scientific Literature
5.	ALA3738334	ADME	Intrinsic clearance in rat liver microsomes at 3 uM	Rattus norvegicus	6	ALA3734684	tissue-based format	Scientific Literature
6.	ALA3738335	ADME	Permeability from apical to basolateral side in MDCK cells at 1 uM	Canis lupus familiaris	3	ALA3734684	cell-based format	Scientific Literature
7.	ALA3738336	ADME	Efflux ratio of permeability from apical to basolateral side to basolateral to apical side in MDCK cells	Canis lupus familiaris	3	ALA3734684	cell-based format	Scientific Literature
8.	ALA3738337	Physicochemical	Kinetic solubility of compound in phosphate buffer saline at pH 7.4		4	ALA3734684	small-molecule physicochemical format	Scientific Literature
9.	ALA3738338	ADME	Fraction unbound in rat brain	Rattus norvegicus	4	ALA3734684	tissue-based format	Scientific Literature
10.	ALA3738340	ADME	Clearance in Sprague-Dawley rat at 0.25 mg/kg, iv	Rattus norvegicus	1	ALA3734684	organism-based format	Scientific Literature
11.	ALA3738342	ADME	Volume of distribution at steady state in Sprague-Dawley rat at 0.25 mg/kg, iv	Rattus norvegicus	1	ALA3734684	organism-based format	Scientific Literature
12.	ALA3738343	ADME	Tmax in Sprague-Dawley rat at 3 mg/kg, po	Rattus norvegicus	3	ALA3734684	organism-based format	Scientific Literature
13.	ALA3738904	ADME	Half life in Sprague-Dawley rat at 3 mg/kg, po	Rattus norvegicus	3	ALA3734684	organism-based format	Scientific Literature
14.	ALA3738905	ADME	Oral bioavailability in Sprague-Dawley rat at 3 mg/kg	Rattus norvegicus	3	ALA3734684	organism-based format	Scientific Literature
15.	ALA3738906	ADME	Cmax in Sprague-Dawley rat plasma at 3 mg/kg, po	Rattus norvegicus	3	ALA3734684	organism-based format	Scientific Literature
16.	ALA3738907	ADME	Brain to plasma ratio in Sprague-Dawley rat at 3 mg/kg, po	Rattus norvegicus	3	ALA3734684	organism-based format	Scientific Literature
17.	ALA3738908	Functional	Cognitive enhancing effect in po dosed rat measured after 4 hrs by novel object recognition test	Rattus norvegicus	3	ALA3734684	organism-based format	Scientific Literature
18.	ALA3738909	Binding	Agonist activity at mGlu receptor (unknown origin)	Homo sapiens	3	ALA3734684	assay format	Scientific Literature
19.	ALA3738910	Binding	Positive allosteric modification of mGlu receptor (unknown origin)	Homo sapiens	3	ALA3734684	assay format	Scientific Literature
20.	ALA3738911	Binding	Negative allosteric modification of mGlu receptor (unknown origin)	Homo sapiens	3	ALA3734684	assay format	Scientific Literature