| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3737385 | Functional | Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux in presence of EC20 glutamate | Homo sapiens | 21 | ALA3734684 | cell-based format | Scientific Literature | |
| 2. | ALA3737386 | Functional | Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as Ca2+ flux upto 25 uM relative to glutamate | Homo sapiens | 20 | ALA3734684 | cell-based format | Scientific Literature | |
| 3. | ALA3738332 | Binding | Positive allosteric modification of mGlu5 receptor in rat cortical astrocytes assessed as maximal leftward shift in the EC50 of glutamate induced response upto 25 uM | Rattus norvegicus | 20 | ALA3734684 | cell-based format | Scientific Literature |
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