# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3736694 | Binding | Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in HEKT cell membrane after 90 mins by scintillation counting method | Homo sapiens | 12 | ALA3734659 | cell-based format | Scientific Literature | |
2. | ALA3736695 | Binding | Displacement of [3H]LSD from human recombinant 5-HT2B receptor stably expressed in HEK cell membrane after 90 mins by scintillation counting method | Homo sapiens | 12 | ALA3734659 | cell-based format | Scientific Literature | |
3. | ALA3736696 | Binding | Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in Flp-IN HEK cell membrane after 90 mins by scintillation counting method | Homo sapiens | 12 | ALA3734659 | cell-based format | Scientific Literature | |
4. | ALA3736697 | Binding | Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in Flp-IN HEK cell membrane at 10 uM after 90 mins by scintillation counting method | Homo sapiens | 11 | ALA3734659 | cell-based format | Scientific Literature | |
5. | ALA3736698 | Binding | Selectivity ratio of Ki for human recombinant 5-HT2A receptor expressed in HEKT cell membrane to Ki for human recombinant 5-HT2B receptor stably expressed in HEK cells | Homo sapiens | 11 | ALA3734659 | cell-based format | Scientific Literature | |
6. | ALA3736699 | Binding | Selectivity ratio of Ki for human recombinant 5-HT2C receptor to Ki for human recombinant 5-HT2B receptor stably expressed in HEK cell membrane | Homo sapiens | 10 | ALA3734659 | cell-based format | Scientific Literature | |
7. | ALA3736700 | Functional | Antagonist activity at human recombinant 5-HT2B receptor expressed in Flp-In HEK cells in the presence of agonist preincubated for 10 mins by FLIPR based calcium mobilization assay | Homo sapiens | 9 | ALA3734659 | cell-based format | Scientific Literature | |
8. | ALA3737567 | Binding | Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in HEKT cell membrane at 10 uM after 90 mins by scintillation counting method | Homo sapiens | 11 | ALA3734659 | cell-based format | Scientific Literature | |
9. | ALA3737568 | Binding | Displacement of [3H]LSD from human recombinant 5-HT2B receptor stably expressed in HEK cell membrane at 10 uM after 90 mins by scintillation counting method | Homo sapiens | 11 | ALA3734659 | cell-based format | Scientific Literature | |
10. | ALA3737569 | Functional | Agonist activity at human recombinant 5-HT2B receptor expressed in Flp-In HEK cells preincubated for 10 mins by FLIPR based calcium mobilization assay | Homo sapiens | 11 | ALA3734659 | cell-based format | Scientific Literature |