| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3737230 | Binding | Inhibition of human recombinant LSD1/CoREST protein expressed in Escherichia coli using monomethylated H3-K4 peptide (21 amino acids) as substrate preincubated for 15 mins followed by substrate addition measured for 12 mins by HRP-coupled Ultrared detection system-based fluorescence analysis | Homo sapiens | 15 | ALA3734732 | assay format | Scientific Literature | |
| 2. | ALA3737231 | Binding | Potency index, ratio of trans-benzyl 1-(4-(2-aminocyclopropyl)phenylamino)-1-oxo-3-phenylpropan-2-ylcarbamate hydrochloride IC50 to compound IC50 for human recombinant LSD1/CoREST protein expressed in Escherichia coli | Homo sapiens | 7 | ALA3734732 | assay format | Scientific Literature | |
| 3. | ALA3737232 | Binding | Inhibition of LSD1 in human NB4 cells assessed as induction of ITGAM mRNA expression at IC50 after 24 hrs by quantitative RT-PCR analysis relative to vehicle-treated control | Homo sapiens | 9 | ALA3734732 | cell-based format | Scientific Literature | |
| 4. | ALA3737235 | Binding | Inhibition of LSD1 in human NB4 cells assessed as induction of GFI-1b mRNA expression at IC50 after 24 hrs by quantitative RT-PCR analysis relative to vehicle-treated control | Homo sapiens | 9 | ALA3734732 | cell-based format | Scientific Literature |
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