# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3737262 | Functional | Antiviral activity against wild type M2 ion channel expressing Influenza A virus (A/Hong Kong/1968(H3N2)) infected in MDCK cells preincubated for 30 mins followed by viral infection measured after 72 hrs by CCK-8 assay | Influenza A virus H3N2 | 10 | ALA3734655 | organism-based format | Scientific Literature | |
2. | ALA3737263 | Functional | Antiviral activity against amantadine-resistant Influenza A virus (A/WSN/1933) infected in MDCK cells preincubated for 30 mins followed by viral infection measured after 72 hrs by CCK-8 assay | Influenza A virus | 9 | ALA3734655 | organism-based format | Scientific Literature | |
3. | ALA3736745 | Functional | Antiviral activity against M2 ion channel S31N mutant expressing amantadine-resistant Influenza A virus infected in MDCK cells preincubated for 30 mins followed by viral infection measured after 72 hrs by CCK-8 assay | Influenza A virus | 9 | ALA3734655 | organism-based format | Scientific Literature | |
4. | ALA3736746 | Functional | Antiviral activity against wild type Influenza A virus (A/Hong Kong/1968(H3N2)) infected in MDCK cells assessed as reduction in size and number of plaque at 1 uM after 2 to 3 days by crystal violet staining based assay | Influenza A virus H3N2 | 1 | ALA3734655 | organism-based format | Scientific Literature | |
5. | ALA3736747 | Functional | Antiviral activity against wild type Influenza A virus (A/Hong Kong/1968(H3N2)) infected in MDCK cells assessed as reduction in size and number of plaque at 0.2 uM after 2 to 3 days by crystal violet staining based assay | Influenza A virus H3N2 | 1 | ALA3734655 | organism-based format | Scientific Literature | |
6. | ALA3736748 | ADME | Cytotoxicity against MDCK cells incubated for 72 hrs by CCK-8 assay | Canis lupus familiaris | 9 | ALA3734655 | cell-based format | Scientific Literature | |
7. | ALA3736749 | Functional | Potency index, ratio of amantadine IC50 to compound IC50 for wild type M2 ion channel expressing Influenza A virus (A/Hong Kong/1968(H3N2)) infected in MDCK cells | Influenza A virus H3N2 | 1 | ALA3734655 | organism-based format | Scientific Literature |