# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3737128 | F | Bactericidal activity against Methicillin sensitive Staphylococcus aureus ATCC 6538 assessed as CFU reduction at 40 uM for 2 hrs under dark condition | Staphylococcus aureus | 3 | ALA3734668 | organism-based format | Scientific Literature | |
2. | ALA3737129 | F | Bactericidal activity against Methicillin resistant Staphylococcus aureus Mu50 assessed as CFU reduction for 1 hr | Staphylococcus aureus | 1 | ALA3734668 | organism-based format | Scientific Literature | |
3. | ALA3737130 | F | Bactericidal activity against Methicillin sensitive Staphylococcus aureus ATCC 6538 assessed as CFU reduction for 1 hr | Staphylococcus aureus | 1 | ALA3734668 | organism-based format | Scientific Literature | |
4. | ALA3737131 | F | Bacteriostatic activity against wild type Staphylococcus aureus 8325-4 | Staphylococcus aureus | 2 | ALA3734668 | organism-based format | Scientific Literature | |
5. | ALA3737132 | F | Bacteriostatic activity against NorA deficient Staphylococcus aureus K1758 | Staphylococcus aureus | 2 | ALA3734668 | organism-based format | Scientific Literature | |
6. | ALA3737133 | F | Bacteriostatic activity against Staphylococcus aureus K2361 overexpressing NorA | Staphylococcus aureus | 2 | ALA3734668 | organism-based format | Scientific Literature | |
7. | ALA3737134 | F | Bacteriostatic activity against MepA deficient Staphylococcus aureus K2908 | Staphylococcus aureus | 2 | ALA3734668 | organism-based format | Scientific Literature | |
8. | ALA3737135 | F | Bacteriostatic activity against Staphylococcus aureus K2068 overexpressing MepA | Staphylococcus aureus | 2 | ALA3734668 | organism-based format | Scientific Literature | |
9. | ALA3737136 | A | Effect on general protein synthesis in Staphylococcus aureus Mu50 at 10 uM measured within 15 hrs | Staphylococcus aureus | 1 | ALA3734668 | organism-based format | Scientific Literature | |
10. | ALA3737137 | F | Reduction in extracellular protein in Staphylococcus aureus Mu50 supernatant at 10 uM measured within 15 hrs | Staphylococcus aureus | 1 | ALA3734668 | organism-based format | Scientific Literature | |
11. | ALA3737138 | F | Potency index, ratio of MIC for vancomysin to MIC for test compound against Methicillin resistant Staphylococcus aureus | Staphylococcus aureus | 1 | ALA3734668 | organism-based format | Scientific Literature | |
12. | ALA3738515 | B | Inhibition of Staphylococcus aureus ATCC 35556 SecA1 expressed in Escherichia coli BL21-gammaDE3 assessed as reduction in intrinsic ATPase activity incubated for 3 hrs measured by malachite green colorimetric method | Staphylococcus aureus | 3 | ALA3734668 | assay format | Scientific Literature | |
13. | ALA3738516 | B | Inhibition of Staphylococcus aureus ATCC 35556 SecA2 expressed in Escherichia coli BL21-gammaDE3 assessed as reduction in intrinsic ATPase activity incubated for 3 hrs measured by malachite green colorimetric method | Staphylococcus aureus | 3 | ALA3734668 | assay format | Scientific Literature | |
14. | ALA3738517 | B | Inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposomal ion channel activity in Xenopus laevis oocytes incubated for 3 hrs measured by recording ion current for 1 min | Staphylococcus aureus | 3 | ALA3734668 | cell-based format | Scientific Literature | |
15. | ALA3738518 | B | Non-competitive inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposomal ATPase activity in Xenopus laevis oocytes incubated for 3 hrs measured by Lineweaver-Burk plot analysis | Staphylococcus aureus | 2 | ALA3734668 | cell-based format | Scientific Literature | |
16. | ALA3738519 | B | Inhibition of Staphylococcus aureus ATCC 35556 SecA1 liposome dependent proOmpA translocation incubated for 1.5 hrs measured by Western blot analysis | Staphylococcus aureus | 1 | ALA3734668 | single protein format | Scientific Literature | |
17. | ALA3738522 | F | Bacteriostatic activity against Staphylococcus aureus ATCC 6538 after 24 hrs | Staphylococcus aureus | 3 | ALA3734668 | organism-based format | Scientific Literature | |
18. | ALA3738523 | B | Inhibition of Staphylococcus aureus SecA1 assessed as reduction in secretion of alpha-hemolysin at 10 uM by Western blot analysis | Staphylococcus aureus | 1 | ALA3734668 | single protein format | Scientific Literature | |
19. | ALA3738524 | B | Inhibition of Staphylococcus aureus SecA1 assessed as reduction in secretion of enterotoxin B at 10 uM by Western blot analysis | Staphylococcus aureus | 1 | ALA3734668 | single protein format | Scientific Literature | |
20. | ALA3738525 | B | Inhibition of Staphylococcus aureus SecA1 assessed as reduction in secretion of TSST-1 at 10 uM by Western blot analysis | Staphylococcus aureus | 1 | ALA3734668 | single protein format | Scientific Literature |