# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3738744 | Binding | Displacement of Ac-[125I]-PACAP27 from recombinant human PAC1 expressed in CHO cells after 90 mins by gamma counting analysis | Homo sapiens | 3 | ALA3734733 | cell-based format | Scientific Literature | |
2. | ALA3738745 | Binding | Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC1 expressed in CHO cells after 90 mins by gamma counting analysis | Homo sapiens | 4 | ALA3734733 | cell-based format | Scientific Literature | |
3. | ALA3738746 | Binding | Displacement of Ac-[125I]-PACAP27 from recombinant human VPAC2 expressed in CHO cells after 90 mins by gamma counting analysis | Homo sapiens | 4 | ALA3734733 | cell-based format | Scientific Literature | |
4. | ALA3738747 | Functional | Neuroprotective activity against MPP+-induced toxicity in human SH-SY5Y cells assessed as increase in cell viability at 100 nM preincubated for 4 hrs followed by incubation with MPP+ for 20 hrs measured after 24 hrs by MTS assay relative to control | Homo sapiens | 3 | ALA3734733 | cell-based format | Scientific Literature | |
5. | ALA3738748 | Binding | Activation of PAC1 in human SH-SY5Y cells assessed as stimulation of forskolin-induced cAMP production at 10'-7 to 10'-5 M after 30 mins | Homo sapiens | 3 | ALA3734733 | cell-based format | Scientific Literature | |
6. | ALA3738749 | Functional | Activation of VPAC1 in human SH-SY5Y cells assessed as stimulation of forskolin-induced cAMP production at 10'-7 to 10'-5 M after 30 mins | Homo sapiens | 3 | ALA3734733 | cell-based format | Scientific Literature | |
7. | ALA3738750 | Functional | Activation of VPAC2 in human SH-SY5Y cells assessed as stimulation of forskolin-induced cAMP production at 10'-7 to 10'-5 M after 30 mins | Homo sapiens | 3 | ALA3734733 | cell-based format | Scientific Literature |