# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3738469 | A | Apparent permeability in human Caco2 cells across basolateral to apical side assessed as drug recovery at 10 uM after 2 hrs | Homo sapiens | 1 | ALA3734753 | cell-based format | Scientific Literature | |
2. | ALA3738470 | A | Apparent permeability in human Caco2 cells across apical to basolateral side assessed as drug recovery at 10 uM after 2 hrs | Homo sapiens | 1 | ALA3734753 | cell-based format | Scientific Literature | |
3. | ALA3738618 | A | Efflux ratio of apparent permeability across apical to basolateral side over basolateral to apical side in human Caco2 cells after 2 hrs | Homo sapiens | 4 | ALA3734753 | cell-based format | Scientific Literature | |
4. | ALA3738619 | B | Inhibition of recombinant rat nNOS D597N/M336V double mutant expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assay | Rattus norvegicus | 2 | ALA3734753 | assay format | Scientific Literature | |
5. | ALA3738620 | A | Apparent permeability in human Caco2 cells across basolateral to apical side at 10 uM after 2 hrs | Homo sapiens | 4 | ALA3734753 | cell-based format | Scientific Literature | |
6. | ALA3738621 | A | Apparent permeability in human Caco2 cells across apical to basolateral side at 10 uM after 2 hrs | Homo sapiens | 4 | ALA3734753 | cell-based format | Scientific Literature | |
7. | ALA3738622 | B | Selectivity ratio of Ki for recombinant rat nNOS D597N/M336V double mutant to Ki for wild type recombinant rat nNOS | Rattus norvegicus | 2 | ALA3734753 | assay format | Scientific Literature | |
8. | ALA3738623 | B | Selectivity ratio of Ki for wild type recombinant rat nNOS to Ki for human nNOS | 9 | ALA3734753 | assay format | Scientific Literature | ||
9. | ALA3738624 | B | Inhibition of recombinant human nNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assay | Homo sapiens | 9 | ALA3734753 | assay format | Scientific Literature | |
10. | ALA3738625 | B | Inhibition of wild type recombinant rat nNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assay | Rattus norvegicus | 19 | ALA3734753 | assay format | Scientific Literature | |
11. | ALA3738626 | B | Inhibition of recombinant murine iNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assay | Mus musculus | 19 | ALA3734753 | assay format | Scientific Literature | |
12. | ALA3738627 | B | Inhibition of recombinant bovine eNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assay | Bos taurus | 19 | ALA3734753 | assay format | Scientific Literature | |
13. | ALA3738628 | B | Selectivity ratio of Ki for wild type recombinant rat nNOS to Ki for murine iNOS | 19 | ALA3734753 | assay format | Scientific Literature | ||
14. | ALA3738629 | B | Selectivity ratio of Ki for wild type recombinant rat nNOS to Ki for bovine eNOS | 19 | ALA3734753 | assay format | Scientific Literature | ||
15. | ALA3738630 | B | Binding affinity to alpha2C adrenergic receptor (unknown origin) | Homo sapiens | 1 | ALA3734753 | single protein format | Scientific Literature | |
16. | ALA3738631 | B | Binding affinity to histamine H2 receptor (unknown origin) | Homo sapiens | 1 | ALA3734753 | single protein format | Scientific Literature | |
17. | ALA3738632 | B | Binding affinity to SERT (unknown origin) | Homo sapiens | 1 | ALA3734753 | single protein format | Scientific Literature |