| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3736726 | A | Metabolic stability in rat liver microsomes after 5 to 180 mins by HPLC-UV analysis | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 2. | ALA3736727 | A | Half life in rat liver microsomes at 100 uM after 5 to 180 mins by HPLC-UV analysis | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 3. | ALA3736728 | T | Acute toxicity in KM mouse assessed as mortality at 677 to 2000 mg/kg, po measured for 4 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA3736729 | T | Acute toxicity in KM mouse assessed as abnormal changes in water consumption at 677 to 2000 mg/kg, po measured for 4 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA3736730 | T | Acute toxicity in KM mouse assessed as abnormal changes in food consumption at 677 to 2000 mg/kg, po measured for 4 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA3736731 | T | Acute toxicity in KM mouse assessed as change in body weight at 677 to 2000 mg/kg, po measured for 14 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA3736732 | T | Acute toxicity in KM mouse assessed as damage to heart at 677 to 2000 mg/kg, po measured on day 14 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA3736733 | T | Acute toxicity in KM mouse assessed as damage to liver at 677 to 2000 mg/kg, po measured on day 14 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA3736734 | T | Acute toxicity in KM mouse assessed as damage to kidney at 677 to 2000 mg/kg, po measured on day 14 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA3736735 | T | Toxicity in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as change in body weight at 30 mg/kg/day administered as intragastric infusion for 32 days measured during compound dosing by Morris water maze assay | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA3736736 | T | Toxicity in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as emesis-like behavior at 30 mg/kg/day administered as intragastric infusion for 32 days measured during compound dosing by Morris water maze assay | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA3736737 | T | Toxicity in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as diarrhea-like behavior at 30 mg/kg/day administered as intragastric infusion for 32 days measured during compound dosing by Morris water maze assay | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA3736738 | T | Toxicity in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as effect on survival at 30 mg/kg/day administered as intragastric infusion for 32 days measured during compound dosing by Morris water maze assay | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA3736739 | F | Cognitive enhancing effect in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as reduction in escape latency at 30 mg/kg/day administered as intragastric infusion for 32 days measured during compound dosing by Morris water maze assay | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA3736740 | F | Cognitive enhancing effect in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as virtual platform crossing at 30 mg/kg/day administered as intragastric infusion for 32 days measured 24 hrs post last dose by Morris water maze assay (Rvb = 2.1 +/- 0.9 No_unit ) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA3736742 | F | Cognitive enhancing effect in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as swimming speed at 30 mg/kg/day administered as intragastric infusion for 32 days measured 24 hrs post last dose by Morris water maze assay (Rvb = 21 +/- 3.1 cm/s ) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA3736744 | F | Cognitive enhancing effect in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as swimming path length in virtual platform at 30 mg/kg/day administered as intragastric infusion for 32 days measured 24 hrs post last dose by Morris water maze assay (Rvb = 10.8 +/- 5.4 cm ) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA3736876 | F | Cognitive enhancing effect in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as time spent in virtual platform at 30 mg/kg/day administered as intragastric infusion for 32 days measured 24 hrs post last dose by Morris water maze assay (Rvb = 0.9 +/- 0.6 secs ) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA3736877 | F | Cognitive enhancing effect in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as swimming path length in effective region at 30 mg/kg/day administered as intragastric infusion for 32 days measured 24 hrs post last dose by Morris water maze assay (Rvb = 72.1 +/- 6 cm ) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA3736879 | F | Cognitive enhancing effect in Wistar rat amyloid beta-induced Alzheimer's disease model assessed as time spent in effective region at 30 mg/kg/day administered as intragastric infusion for 32 days measured 24 hrs post last dose by Morris water maze assay (Rvb = 3.3 +/- 1.1 secs ) | Rattus norvegicus | 2 | organism-based format | Scientific Literature |
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