| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3738667 | ADME | Cytotoxicity against human MT4 cells assessed as reduction in cell proliferation after 96 hrs by MTT assay | Homo sapiens | 28 | ALA3734708 | cell-based format | Scientific Literature | |
| 2. | ALA3738668 | Functional | Antiviral activity against HIV-1 3B infected in human MT4 cells assessed as protection against virus-induced cytopathic effect after 4 days by MTT assay | Human immunodeficiency virus 1 | 28 | ALA3734708 | organism-based format | Scientific Literature | |
| 3. | ALA3738669 | ADME | Cytotoxicity against MDBK cells assessed as reduction in cell viability after 72 hrs by MTT assay | Bos taurus | 28 | ALA3734708 | cell-based format | Scientific Literature | |
| 4. | ALA3738670 | Functional | Antiviral activity against BVDV NADL ATCC VR-534 infected in MDBK cells assessed as protection against virus-induced cytopathic effect after 3 or 4 days by MTT assay | Bovine viral diarrhea virus 1 | 27 | ALA3734708 | organism-based format | Scientific Literature | |
| 5. | ALA3738671 | ADME | Cytotoxicity against BHK21 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Mesocricetus auratus | 28 | ALA3734708 | cell-based format | Scientific Literature | |
| 6. | ALA3738672 | Functional | Antiviral activity against YFV 17-D vaccine (Stamaril Pasteur J07B01) infected in BHK21 cells assessed as protection against virus-induced cytopathic effect after 3 or 4 days by MTT assay | Yellow fever virus | 28 | ALA3734708 | organism-based format | Scientific Literature | |
| 7. | ALA3738673 | Functional | Antiviral activity against Reovirus 1 ATCC VR- 214 infected in BHK21 cells assessed as protection against virus-induced cytopathic effect after 3 or 4 days by MTT assay | Mammalian orthoreovirus 1 | 29 | ALA3734708 | cell-based format | Scientific Literature | |
| 8. | ALA3738674 | ADME | Cytotoxicity against african green monkey Vero 76 cells assessed as reduction in cell viability after 48 to 96 hrs by MTT assay | Chlorocebus sabaeus | 28 | ALA3734708 | cell-based format | Scientific Literature | |
| 9. | ALA3738675 | Functional | Antiviral activity against CVB-5 virus Faulkner ATCC VR-185 infected in african green monkey Vero-76 cells after 3 days by plaque reduction assay | Coxsackievirus B5 | 31 | ALA3734708 | organism-based format | Scientific Literature | |
| 10. | ALA3738676 | Functional | Antiviral activity against Human poliovirus 1 strain Sabin 1 virus infected in african green monkey Vero-76 cells after 2 days by plaque reduction assay | Human poliovirus 1 strain Sabin | 28 | ALA3734708 | organism-based format | Scientific Literature | |
| 11. | ALA3738677 | Functional | Antiviral activity against RSVA2 ATCC VR-1540 infected in african green monkey Vero-76 cells after 5 days by plaque reduction assay | Respiratory syncytial virus | 28 | ALA3734708 | organism-based format | Scientific Literature | |
| 12. | ALA3738678 | Functional | Antiviral activity against VSV Indiana ATCC VR-158 infected in african green monkey Vero-76 cells after 2 days by plaque reduction assay | Vesicular stomatitis virus | 28 | ALA3734708 | organism-based format | Scientific Literature | |
| 13. | ALA3738679 | Functional | Antiviral activity against VV Elstree ATCC VR-1549 infected in african green monkey Vero-76 cells after 3 days by plaque reduction assay | Vaccinia virus | 28 | ALA3734708 | organism-based format | Scientific Literature | |
| 14. | ALA3738680 | Functional | Antiviral activity against HSV-1 KOS ATCC VR- 1493 infected in african green monkey Vero-76 cells after 3 days by plaque reduction assay | Human alphaherpesvirus 1 | 28 | ALA3734708 | organism-based format | Scientific Literature | |
| 15. | ALA3736639 | Binding | Inhibition of BVDV RNA-dependent RNA polymerase pre-incubated for preincubated for 30 mins before GTP addition and measured after 120 mins by fluorescence based microplate reader assay | Bovine viral diarrhea virus 1 | 1 | ALA3734708 | assay format | Scientific Literature | |
| 16. | ALA3813544 | Functional | Antiviral activity against BVDV NADL infected in MDBK cells assessed as inhibition of virus induced cytopathogenicity after 3 to 4 days by MTT assay | Bovine viral diarrhea virus 1-NADL | 35 | ALA3808296 | cell-based format | Scientific Literature | |
| 17. | ALA3813546 | Binding | Inhibition of His tagged BVDV NS5B Cdelta24 RNA dependent RNA polymerase expressed in Escherichia coli Rosetta DE3 preincubated for 30 mins followed by addition of GTP measured after 120 mins by fluorescence analysis | Bovine viral diarrhea virus 1 | 5 | ALA3808296 | assay format | Scientific Literature | |
| 18. | ALA3813547 | Binding | Inhibition of His tagged BVDV NS5B Cdelta24 RNA dependent RNA polymerase K263A mutant expressed in Escherichia coli Rosetta DE3 preincubated for 30 mins followed by addition of GTP measured after 120 mins by fluorescence analysis | Bovine viral diarrhea virus 1 | 5 | ALA3808296 | assay format | Scientific Literature | |
| 19. | ALA3812807 | Binding | Inhibition of His tagged BVDV NS5B Cdelta24 RNA dependent RNA polymerase R295A mutant expressed in Escherichia coli Rosetta DE3 preincubated for 30 mins followed by addition of GTP measured after 120 mins by fluorescence analysis | Bovine viral diarrhea virus 1 | 5 | ALA3808296 | assay format | Scientific Literature | |
| 20. | ALA3812808 | Binding | Inhibition of His tagged BVDV NS5B Cdelta24 RNA dependent RNA polymerase Y674A mutant expressed in Escherichia coli Rosetta DE3 preincubated for 30 mins followed by addition of GTP measured after 120 mins by fluorescence analysis | Bovine viral diarrhea virus 1 | 5 | ALA3808296 | assay format | Scientific Literature |
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