| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3738193 | B | Inhibition of recombinant N-terminal His6-tagged KAT8 (unknown origin) expressed in Escherichia Coli BL21 DE3 cells assessed as reduction of Co A level using histone H4 substrate at 400 uM after 15 mins by CPM fluorescence assay | Homo sapiens | 10 | ALA3734689 | cell-based format | Scientific Literature | |
| 2. | ALA3738205 | B | Inhibition of recombinant N-terminal His6-tagged KAT8 (unknown origin) expressed in Escherichia Coli BL21 DE3 cells assessed as reduction of Co A level using histone H4 substrate after 15 mins by CPM fluorescence assay | Homo sapiens | 10 | ALA3734689 | cell-based format | Scientific Literature | |
| 3. | ALA3738206 | B | Inhibition of human recombinant Histone acetyltransferase p300 catalytic domain (1284-1672 residues) using [3H]Acetyl-CoA and histone H3 substrate at 50 uM after 1 hr by liquid scintillation counting | Homo sapiens | 10 | ALA3734689 | single protein format | Scientific Literature | |
| 4. | ALA4192129 | B | Inhibition of VMA intein chitin binding domain-fused p300 HAT domain (1287 to 1652 residues) (unknown origin) expressed in Escherichia coli BL21(RIL)-DE3 using H4-15 and acetyl-coA as substrate preincubated for 10 mins followed by substrate addition in presence of NAD by alpha-ketoglutarate dehydrogenase enzyme coupled spectrophotometric assay | Homo sapiens | 1 | ALA4190249 | assay format | Scientific Literature | |
| 5. | ALA4192133 | B | Inhibition of p300 (unknown origin) using H3 peptide and acetyl-coA as substrate by fluorometric assay | Homo sapiens | 8 | ALA4190249 | single protein format | Scientific Literature | |
| 6. | ALA4192136 | F | Anticlonogenic activity against human A549 cells after 10 days | Homo sapiens | 1 | ALA4190249 | cell-based format | Scientific Literature | |
| 7. | ALA4192137 | F | Anticlonogenic activity against human NCI-H157 cells after 10 days | Homo sapiens | 1 | ALA4190249 | cell-based format | Scientific Literature | |
| 8. | ALA4192138 | F | Anticlonogenic activity against human NCI-H460 cells after 10 days | Homo sapiens | 1 | ALA4190249 | cell-based format | Scientific Literature | |
| 9. | ALA4192139 | F | Antiproliferative activity against human A549 cells at 0.1 to 10 uM after 96 hrs by WST8 assay | Homo sapiens | 5 | ALA4190249 | cell-based format | Scientific Literature | |
| 10. | ALA4269227 | B | Inhibition of P300 (unknown origin) | Homo sapiens | 1 | ALA4265983 | single protein format | Scientific Literature | |
| 11. | ALA4407058 | B | Inhibition of P300 (unknown origin) (1287 to 1652 residues) expressed in Escherichia coli BL21(RIL)-DE3 cells using [12C]-acetyl-CoA/[14C]-acetyl-CoA as substrate after 10 mins | Homo sapiens | 1 | ALA4406797 | cell-based format | Scientific Literature | |
| 12. | ALA4407087 | B | Inhibition of P300 BHC domain (unknown origin) | Homo sapiens | 1 | ALA4406797 | single protein format | Scientific Literature | |
| 13. | ALA4407088 | B | Inhibition of CBP BHC domain (unknown origin) | Homo sapiens | 1 | ALA4406797 | single protein format | Scientific Literature | |
| 14. | ALA4407090 | B | Noncompetitive inhibition of P300 (1287 to 1652 residues) VMA intein chitin binding domain (unknown origin) expressed in Escherichia coli BL21(RIL)-DE3 cells using H4-15 as substrate | Homo sapiens | 1 | ALA4406797 | cell-based format | Scientific Literature |
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